 | | Vol. 13.25 – 15 July, 2021 |
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| Scientists reported a comprehensive comparison of human MSCs derived from umbilical cord Wharton’s jelly, dental pulp, and adipose tissue on the treatment of glucose and lipid metabolic disorders in type II diabetic mice.
[Stem Cell Research & Therapy] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers compared the cytoprotection between peritoneal dialysis (PD) effluent-derived MSCs and umbilical cord-derived MSCs in the treatment of both peritoneal membrane and kidney injury in uremic rats with chronic PD.
[Stem Cell Research & Therapy] |
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| Scientists performed a landmark study comparing long-term outcomes in acute myeloid leukemia (AML) patients alive and disease-free two years after transplantation who received grafts from either cord blood transplantation or unrelated donors.
[Bone Marrow Transplantation] |
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| The authors described their cord blood bank’s novel collection technique, which involved both in utero and ex utero collection of a single cord blood unit. They also evaluated maternal, neonatal and collection parameters that may have impacted the cell dose.
[Cytotherapy] |
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| Using a cohort of 66 COVID-19-positive women in late pregnancy, scientists correlated clinical parameters with disease severity, placental histopathology, and the expression of viral entry and Interferon-induced transmembrane antiviral transcripts.
[Scientific Reports] |
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| Investigators successfully generated a 3D placental organ bud from human induced-pluripotent cells, which differentiated into various lineages of trophoblasts such as cytotrophoblast-like, syncytiotrophoblast-like, and extravillous trophoblast-like cells, forming organized layers in the bud.
[Scientific Reports] |
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| Exosome marker protein levels were increased in the exosomes derived from human umbilical cord MSCs (hUMSC-Ex) compared with those in hUMSC suspension, indicating that exosomes were successfully isolated from hUMSCs.
[Acta Biochimica et Biophysica Sinica] |
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| Since umbilical cord (UC)-MSCs have few human leukocyte antigen-II and major histocompatibility complex class I molecules, and are easy to isolate and culture, UC-MSC sheets have been proposed as a candidate for clinical applications to ischemic heart disease.
[Stem Cell Research & Therapy] |
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| Amniotics AB has raised SEK60 million through its recent listing on Nasdaq. The funds will now be deployed to advance the company’s preclinical portfolio of cell therapy candidates based on MSC from amniotic fluid. Lead candidate PulmoStem™, a first-in-class treatment for pulmonary disease is scheduled to enter the clinic.
[Amniotics AB] |
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| September 20 – 23, 2021
Virtual |
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| | GSK – Moon Township, Pennsylvania, United States |
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| | Medical University of South Carolina – Charleston, South Carolina, United States |
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| | Stanford University – Palo Alto, California, United States |
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| | FibroBiologics – Houston, Texas, United States |
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| | UT Southwestern Medical Center – Dallas, Texas, United Statess |
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