Cord Blood News Volume 13.27 | Jul 29 2021

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    2021-07-29 | CBN 13.27


    Cord Blood News by STEMCELL Technologies
    Vol. 13.27 – 29 July, 2021
    TOP STORY

    Firefly Luciferase Offers Superior Performance to AkaLuc for Tracking the Fate of Administered Cell Therapies

    Umbilical cord MSCs were transduced to produce two genetically engineered populations, expressing either AkaLuc or the engineered firefly luciferase luc2.
    [European Journal of Nuclear Medicine and Molecular Imaging]

    Full Article

    Dr. Fabio Rossi discusses the role of mesenchymal stem cells in tissue repair and development.
    PUBLICATIONSRanked by the impact factor of the journal

    Cord Blood Group 2 Innate Lymphoid Cells Are Associated with Lung Function at Six Weeks of Age

    Researchers investigated cord blood immune cell populations from babies born to mothers with asthma in pregnancy.
    [Clinical & Translational Immunology]

    Full Article

    The Use of Umbilical Cord-Derived Mesenchymal Stem Cells in Patients with Muscular Dystrophies: Results from Compassionate Use in Real-Life Settings

    The authors administered advanced therapy medicinal product containing umbilical cord-derived MSCs to 22 patients with muscular dystrophies.
    [Stem Cells Translational Medicine]

    Full Article

    CHIP-Overexpressing Wharton’s Jelly-Derived Mesenchymal Stem Cells Attenuate Hyperglycemia-Induced Oxidative Stress-Mediated Kidney Injuries in Diabetic Rats

    Western blot analysis, flow cytometry, and MitoSOX staining revealed that hyperglycemia-induced mitochondrial oxidative stress production and apoptosis were attenuated in CHIP-overexpressing Wharton’s jelly-derived MSCs.
    [Free Radical Biology and Medicine]

    AbstractGraphical Abstract

    Mesenchymal Stem Cell-Derived Extracellular Vesicles as Probable Triggers of Radiation-Induced Heart Disease

    Scientists examined the hypothesis that the altered secretion of extracellular vesicles from MSCs was the trigger of radiation-induced heart disease.
    [Stem Cell Research & Therapy]

    Full Article

    Unresponsive Thin Endometrium Caused by Asherman Syndrome Treated with Umbilical Cord Mesenchymal Stem Cells on Collagen Scaffolds: A Pilot Study

    Researchers evaluated the effect of transplantation with collagen scaffold/umbilical cord MSCs on Asherman syndrome.
    [Stem Cell Research & Therapy]

    Full Article

    Molecular Evidence Suggesting the Persistence of Residual SARS-CoV-2 and Immune Responses in the Placentas of Pregnant Patients Recovered from COVID-19

    The authors assessed SARS-CoV-2 nucleic acid and protein retention in the placentas of pregnant women who had fully recovered from COVID-19 and cytokine fluctuations in maternal and fetal tissues.
    [Cell Proliferation]

    Full Article

    Lymphoid and Myeloid Immune Cell Reconstitution after Nicotinamide-Expanded Cord Blood Transplantation

    Investigators evaluated the immune reconstitution (IR) of patients receiving omidubicel grafts during the first six months post-hematopoietic cell transplantation, as IR was critical for favorable outcomes of the procedure.
    [Bone Marrow Transplantation]

    Full Article

    Embelin Downregulated cFLIP in Breast Cancer Cell Lines Facilitate Anti-Tumor Effect of IL-1β-Stimulated Human Umbilical Cord Mesenchymal Stem Cells

    Scientists found that IL-1β-stimulated human umbilical cord-derived MSCs enhanced the expression of membrane-bound and soluble tumor necrosis factor-related apoptosis-inducing ligand.
    [Scientific Reports]

    Full Article

    Get High Cell Purity and Recovery with Lymphoprepâ„¢
    REVIEWS

    Pregnancy and Pandemics: Interaction of Viral Surface Proteins and Placenta Cells

    The authors display information on Variola, Influenza, Zika and Corona viruses focused on their surface proteins, effects on pregnancy, and possible target placental cells.
    [Biochimica et Biophysica Acta]

    Abstract

    INDUSTRY AND POLICY NEWS

    State Gives $51 Million to College Students for Stem Cell Research

    The California stem cell agency awarded $51 million to help train students in the art of research at the Golden State’s community colleges and universities.
    [Capitol Weekly]

    Press Release

    FEATURED EVENT

    Cambridge Cancer Epigenetics Club: JJ Schuringa

    October 15, 2021
    Virtual

    > See All Events

    JOB OPPORTUNITIES

    Postdoctoral Positions – Stem Cell-Based Therapy

    UCLA Jules Stein Eye Institute – Los Angeles, California, United States

    Postdoctoral Fellow – Cancer Genomics and Liquid Biopsies

    University of Gothenburg – Gothenburg, Sweden

    Postdoctoral Position – Leukemia

    Princess Margaret Cancer Centre – Toronto, Ontario, United States

    Research Assistant – Immunobiology of MSCs

    Mercer University – Savannah, Georgia, United States

    Assistant, Associate, or Full Professor – Stem Cell Biology and Regenerative/Restorative Medicine

    Stanford University – Palo Alto, California, United States

    > See All Jobs

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