| Vol. 13.28 – 5 August, 2021 |
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| Scientists investigated if MSCs derived from the amniotic membrane could support the ex vivo expansion of hematopoietic stem cell and progenitor cells. [Stem Cells Translational Medicine] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Using two different kinds of invasion assays, this study aimed at investigating and characterizing the 3D migratory capacity of human amniotic fluid stem cells, a well-established fetal stem cell type. [Stem Cells] |
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| The authors examined the effect human amniotic epithelial cells had on the liver progenitor cell response and hepatic oxidative stress in an experimental model of non-alcoholic steatohepatitis. [Stem Cell Research & Therapy] |
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| Investigators evaluated the clinical outcome of severe/critically severe 210 COVID-19 patients treated with umbilical cord-MSCs. [Stem Cell Reviews and Reports] |
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| Human umbilical cord MSC-derived exosomes carrying miR-378a-5p inhibited NLRP3 inflammasomes and abrogated cell pyroptosis to protect against dextran sulfate sodium-induced colitis. [Stem Cell Research & Therapy] |
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| Natural killer cells were isolated from human umbilical cord blood from a healthy newborn and reprogrammed by episomal vectors carrying reprograming factors L-MYC, LIN28, OCT4, SOX2, KLF4, EBNA-1, and shRNA against p53 delivered using nucleofection. [Stem Cell Research] |
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| A model of HTLV-1 and S. stercoralis coinfection in CD34+ umbilical cord blood hematopoietic stem cell engrafted humanized mice was established. [PLOS Neglected Tropical Diseases] |
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| Researchers evaluated intratracheal MSCs as an approach to treat an hyperoxia-induced bronchopulmonary dysplasia animal model and compared the therapeutic effects between amniotic fluid-, umbilical cord- and bone marrow-MSCs. [Journal of Cellular and Molecular Medicine] |
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| | | The authors present a critical analysis of the risks, limitations, challenges, and opportunities that place MSC-based products as a therapeutic strategy that may complement the current arsenal against COVID-19 and reduce the pandemic’s unmet medical needs. [Stem Cell Research & Therapy] |
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| | | Hope Biosciences Stem Cell Research Foundation has received FDA authorization for a randomized, double-blind, single center, Phase II clinical trial to assess the efficacy of multiple intravenous infusions of autologous adipose-derived MSCs in improving symptoms and quality of life in patients with mild-to-moderate multiple sclerosis. [Hope Biosciences Stem Cell Research Foundation (BusinessWire, Inc.)] |
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| | | October 28 – 29, 2021 Virtual |
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| | | | UCLA Jules Stein Eye Institute – Los Angeles, California, United States |
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| | University of Gothenburg – Gothenburg, Sweden |
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| | Princess Margaret Cancer Centre – Toronto, Ontario, United States |
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| | Mercer University – Savannah, Georgia, United States |
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| | Dalhousie University – Halifax, Nova Scotia, Canada |
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