Cord Blood News Volume 13.30 | Aug 19 2021

    By
    Justin.choi
    -
    0
    108







    2021-08-19 | CBN 13.30


    Cord Blood News by STEMCELL Technologies
    Vol. 13.30 – 19 August, 2021
    TOP STORY

    Colony Forming Potential and Protein Composition of Commercial Umbilical Cord Allograft Products in Comparison with Autologous Orthobiologics

    Investigators evaluated commercial umbilical cord allograft products for viable cells, colony forming unit–fibroblasts, and protein makeup.
    [American Journal of Sports Medicine]

    Abstract


    Getting enough cord blood HSCs for transplantation isn't easy. But she's paving the way. Watch Suzan Imren's webinar.
    PUBLICATIONSRanked by the impact factor of the journal

    Microsphere Embedded Hydrogel Construct – Binary Delivery of Alendronate and BMP-2 for Superior Bone Regeneration

    A microsphere embedded osteoinductive decellularized bone ECM/oleoyl chitosan based hydrogel construct was developed as a matrix allowing dual delivery of an anti-resorptive drug and BMP-2 for a focal tibial defect in a rabbit model. Amniotic membrane-derived stem cells cultivated on the hydrogel construct demonstrated excellent biocompatibility, cell viability, and active proliferation potential.
    [Journal of Materials Chemistry B]

    AbstractGraphical Abstract

    Comparative Analysis of Human Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells and Umbilical Cord Mesenchymal Stem Cells

    Researchers compared the therapeutic potential of induced pluripotent stem cells differentiation into MSCs generated from urinary epithelial cells with the available umbilical cord MSCs.
    [Journal of Cellular and Molecular Medicine]

    Full Article

    Human Umbilical Cord Mesenchymal Stem Cells-Derived Extracellular Vesicles Facilitate the Repair of Spinal Cord Injury via the miR-29b-3p/PTEN/Akt/mTOR Axis

    Investigators explored the repair effect of human umbilical cord MSCs-derived extracellular vesicles on spinal cord injury.
    [Cell Death Discovery]

    Full Article

    CGF Membrane Promotes Periodontal Tissue Regeneration Mediated by hUCMSCs through Upregulating TAZ and Osteogenic Differentiation Genes

    Scientists explored the role of concentrated growth factor membranes in periodontal tissue regeneration mediated by human umbilical cord MSCs.
    [Stem Cells International]

    Full Article

    SA/G Hydrogel Containing NRF2-Engineered HEK-293-Derived CM Improves Wound Healing Efficacy of WJ-MSCs in a Rat Model of Excision Injury

    The authors revealed that the NRF2-conditioned medium protected the wharton’s jelly derived-MSCs against H2O2-induced toxicity in vitro.
    [Journal of Tissue Viability]

    Abstract

    Scientific resources to support your hematopoiesis research. Learn More!
    REVIEWS

    Clinical Trials Based on Mesenchymal Stromal Cells are Exponentially Increasing: Where are We in Recent Years?

    Most of the 416 published trials evaluated MSCs’ effectiveness in treating cardiovascular diseases, GvHD, and brain and neurological disorders, although some trials sought to treat immune system diseases and wounds and to restore tissue.
    [Stem Cell Reviews and Reports]

    Full ArticleGraphical Abstract

    Stem Cells for Aging-Related Disorders

    Scientists explore the potential of transplanting exogenous umbilical cord blood cells and mobilizing host resident stem cells in vascular dementia and aging.
    [Stem Cell Reviews and Reports]

    Abstract

    INDUSTRY AND POLICY NEWS

    ERS Genomics and Cellular Engineering Technologies Enter CRISPR/Cas9 License Agreement

    ERS Genomics Limited announced a non-exclusive license agreement granting CET access to ERS Genomics’ CRISPR/Cas9 patent portfolio.
    [ERS Genomics Limited]

    Press Release

    FEATURED EVENT

    American Association of Blood Banks (AABB)

    October 17 – 19, 2021
    Virtual

    > See All Events

    JOB OPPORTUNITIES

    Postdoctoral Associate – Stem/Progenitor Cells

    Baylor College of Medicine – Houston, Texas, United States

    Development Engineer – Cell Therapies and Regenerative Medicine

    Danaher – Toronto, Ontario, Canada

    Research Associate – Stem Cell Models

    Michigan State University – East Lansing, Michigan, United States

    Postdoctoral Positions – Stem Cell-Based Therapy

    UCLA Jules Stein Eye Institute – Los Angeles, California, United States

    Postdoctoral Position – Leukemia

    Princess Margaret Cancer Centre – Toronto, Ontario, United States

    > See All Jobs

    Submit an article, publication, job or event
    Brought to you by
    stemcell-logo-for newsletter-2
    Cord Blood News Twitter