 | | Vol. 13.32 – 2 September, 2021 |
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| Investigators reported that the frequencies of SCID repopulating cells were greatly decreased in cord blood CD34+ hematopoietic stem cells and hematopoietic progenitor cells upon ex vivo culture.
[Journal of Clinical Investigation] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| A rabbit alveolar process cleft model was established by removing the bone tissue from the left maxillary bone. 48 young Japanese white rabbits were divided into normal, control, material and mesenchymal stem cell groups.
[Stem Cell Reviews and Reports] |
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| Researchers investigated whether coadministration with pimecrolimus, one of the topical calcineurin inhibitors, could influence the therapeutic potential of human umbilical cord blood MSCs in atopic dermatitis.
[Stem Cell Research & Therapy] |
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| The authors investigated the safety for clinic use and therapeutic effects of basic fibroblast growth factor-overexpressing human umbilical cord-derived MSCs in mice with completely transected spinal cord injury.
[Stem Cell Research & Therapy] |
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| Scientists investigated whether there is the combined effect between di (2-ethylhexyl) phthalate and 50-Hz magnetic fields on cell proliferation in human amniotic cells.
[Ecotoxicology and Environmental Safety] |
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| This study was designed to lay the preliminary foundations for future cell-based therapy for patients with severe factor V deficiency.
[Biomedicine & Pharmacotherapy] |
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| Researchers evaluated outcomes in patients with hematological malignancy treated with myeloablative conditioning prior to haplo or umbilical cord blood hematopoietic stem cell transplantation.
[Blood Advances] |
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| Investigators demonstrated that prime or prime-boost administration of mRNA-1273 in hamsters elicited robust neutralizing antibodies, ameliorated weight loss, suppressed SARS-CoV-2 replication in the airways, and better protected against disease at the highest prime-boost dose.
[Journal of Clinical Investigation] |
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| Researchers highlighted the importance of regional public cord blood banks in fulfilling hematopoietic stem cell transplantation needs, especially in countries with significant genetic diversity.
[Cytotherapy] |
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| Human umbilical cord-derived MSCs effectively decreased the incidence and severity of graft-versus-host disease (GVHD), which was mediated by the enrichment of myeloid-derived suppressor cells in GVHD target tissues.
[Cytotherapy] |
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| The authors aimed to identify the S-nitrosylated proteins induced by adrenomedullin in the JEG-3 placental cells.
[Reproductive Sciences] |
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| One therapeutic approach showing a ray of hope to combat COVID-19 infection is MSC therapy. Mesenchymal cells have immunomodulatory, anti-inflammatory as well as regenerative properties and various preliminary studies have shown that MSCs can reverse the lung damage and overcome the cytokine storm incited by COVID-19 infection.
[Life Sciences] |
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| The governing Board of the California Institute for Regenerative Medicine has approved a trio of awards, totaling approximately $4 million, to University of California San Diego School of Medicine researchers to advance studies of new stem cell-based treatments for multiple types of cancer and amyotrophic lateral sclerosis.
[UC San Diego Health] |
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| A University of Miami Miller School of Medicine research team has launched a Phase III multicenter clinical trial to evaluate the effectiveness of mesenchymal stem cells in treating COVID-19 patients with acute respiratory distress syndrome.
[University of Miami] |
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| September 24 – 27, 2021
Kloster Seeon, Germany |
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| | Banner MD Anderson Cancer Center – Gilbert, Arizona, United States |
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| | Indiana University – Indianapolis, Indiana, United States |
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| | Baylor College of Medicine – Houston, Texas, United States |
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| | Michigan State University – East Lansing, Michigan, United States |
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| | Danaher – Toronto, Ontario, Canada |
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