Cord Blood News Volume 13.33 | Sep 9 2021

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    2021-09-09 | CBN 13.33


    Cord Blood News by STEMCELL Technologies
    Vol. 13.33 – 9 September, 2021
    TOP STORY

    Mitogen-Activated Protein Kinase Signaling in Childhood Asthma Development and Environment-Mediated Protection

    Scientists aimed to investigate the role of MAPK signaling in childhood asthma and its environment-mediated protection, including a representative selection of 232 out of 1062 children from two cross-sectional cohorts and one birth cohort study.
    [Pediatric Allergy and Immunology]

    Abstract

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    A Novel Study on the Immunomodulatory Effect of Umbilical Cord Derived Mesenchymal Stem Cells Pretreated with Traditional Chinese Medicine Asarinin

    To better understand the role of MSC in the prevention and treatment of graft-versus-host disease, umbilical cord derived MSCs were pre-treated with Chinese medicine Asarinin and IFN-γ.
    [International Immunopharmacology]

    Full Article

    CML Derived Exosomes Promote Tumor Favorable Functional Performance in T Cells

    Human primary cord blood-derived T cells were treated with K562-derived exosomes. Scientists evaluated the expression variation of some critical genes activated in suppressor T cells.
    [BMC Cancer]

    Full Article

    The Protective Benefit of Heme Oxygenase-1 Gene Modified Human Placenta-Derived Mesenchymal Stem Cell in N-Nitro-L-Arginine Methyl Ester -Induced Preeclampsia-Like Rat Model: Possible Implications for Placental Angiogenesis

    Investigators explored the protective benefit of heme oxygenase-1-placenta-derived MSC transplantation in a preeclampsia-like rat model.
    [Stem Cells and Development]

    Abstract

    Tracking of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells in Premature Ovarian Failure Model Mice

    The authors evaluated the migration and distribution of embryonic stem cell-derived MSCs in a model of chemotherapy-induced premature ovarian failure.
    [Biochemical and Biophysical Research Communications]

    Abstract

    Phenotypic, Morphological, and Metabolic Characterization of Vascular-Spheres from Human Vascular Mesenchymal Stem Cells

    Scientists tested the ability of human MSCs isolated from the vascular wall to grow as spheres, and provide a characterization of this 3D model.
    [Microscopy Research and Technique]

    Full Article

    Webinar: Bone Marrow Skeletal Progenitors and Bone Diseases
    REVIEWS

    Mesenchymal Stem Cell Therapy for Severe COVID-19

    Investigators summarize the recent progress in MSC therapy for COVID-19 and highlight the challenges in the field.
    [Signal Transduction and Targeted Therapy]

    Full Article

    INDUSTRY AND POLICY NEWS

    BioRestorative Therapies Receives Patent in Japan Related to its Off-the-Shelf ThermoStem® Program

    BioRestorative Therapies, Inc. announced that the Japanese Patent Office has issued the company a patent related to its metabolic ThermoStem® Program. Claims granted under the new patent cover methodologies related to brown adipocytes from human brown adipose-derived stem cells.
    [BioRestorative Therapies, Inc. (GlobeNewswire, Inc.)]

    Press Release

    Sorrento Announces Enrollment of First Subject in Brazil Phase II Study of COVI-MSC for Treatment of COVID-19 Associated Acute Respiratory Distress in ICU Patients

    Sorrento Therapeutics, Inc. announced the start of enrollment in its Phase II efficacy study of human allogeneic adipose-derived mesenchymal stem cells for patients suffering from COVID-19-induced acute respiratory distress or acute respiratory distress syndrome in Brazil.
    [Sorrento Therapeutics, Inc.]

    Press Release

    FEATURED EVENT

    Annual London Stem Cell Network Symposium

    October 19, 2021
    London, England, United Kingdom

    > See All Events

    JOB OPPORTUNITIES

    Postdoctoral Fellow – Hematopoietic and Mesenchymal Cells

    Lund University – Lund, Sweden

    Advanced Practice Provider – Stem Cell Transplantation

    Banner MD Anderson Cancer Center – Gilbert, Arizona, United States

    Postdoctoral Fellow – Normal and Leukemic Hematopoietic Stem Cells

    Indiana University – Indianapolis, Indiana, United States

    Postdoctoral Associate – Stem/Progenitor Cells

    Baylor College of Medicine – Houston, Texas, United States

    Development Engineer – Cell Therapies and Regenerative Medicine

    Danaher – Toronto, Ontario, Canada

    > See All Jobs

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