Cord Blood News Volume 13.42 | Nov 25 2021

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    2021-11-25 | CBN 13.42


    Cord Blood News by STEMCELL Technologies
    Vol. 13.42 – 25 November, 2021
    TOP STORY

    Comparing Cord Blood Transplantation and Matched Related Donor Transplantation in Non-Remission Acute Myeloid Leukemia

    Scientists investigated the impact of cord blood transplantation, and compared to human leukocyte antigen-matched related donor transplantation.
    [Leukemia]

    Full Article

    Image of erythroblasts which were simply & efficiently generated from PSCs using the STEMdiff Erythroid Kit.
    PUBLICATIONSRanked by the impact factor of the journal

    Prospective Associations of Early Pregnancy Metal Mixtures with Mitochondria DNA Copy Number and Telomere Length in Maternal and Cord Blood

    Researchers evaluated individual and joint associations of prenatal metals with mitochondrial DNA copy number and telomere length in maternal and cord blood as biomarkers of inflammation and oxidative stress.
    [Environmental Health Perspectives]

    Full Article

    LncRNA MEG3 Alleviates PFOS Induced Placental Cell Growth Inhibition through Its Derived miR-770 Targeting PTX3

    Scientists investigated the function of long non-coding RNA MEG3 and its derived miR-770 in perfluorooctane sulfonic acid (PFOS)-induced placental toxicity.
    [Environmental Pollution]

    AbstractGraphical Abstract

    Prenatal Metal Exposure, Cord Blood DNA Methylation and Persistence in Childhood: An Epigenome-Wide Association Study of 12 Metals

    Researchers analyzed the extent to which metals measured in maternal erythrocytes were associated with differentially methylated positions and regions in cord blood and tested if associations persisted in blood collected in mid-childhood.
    [Clinical Epigenetics]

    Full Article

    Developing a Pro-Angiogenic Placenta Derived Amniochorionic Scaffold with Two Exposed Basement Membranes as Substrates for Cultivating Endothelial Cells

    An optimized combination of enzymatic solutions with mechanical scrapping was used to remove the amniotic epithelium and chorion trophoblastic layer of a placenta membrane, which resulted in exposing the basement membranes of both sides without their separation and subsequent damages to the in-between spongy layer.
    [Scientific Reports]

    Full Article

    Prenatal Exposure to Poly-/Per-Fluoroalkyl Substances Is Associated with Alteration of Lipid Profiles in Cord-Blood

    Researchers combined determination of bile acids and molecular lipids by liquid chromatography with ultra-high-resolution mass spectrometry, and separately quantified cord blood concentrations of sixteen poly-/per-fluoroalkyl substances in a cohort of Chinese infants.
    [Metabolomics]

    Abstract

    Resources for Your T Cell Therapy Research
    REVIEWS

    The Coevolution of Placentation and Cancer

    The authors conclude that many similarities between trophoblast and cancer cells are shared with other, phylogenetically older processes than placentation.
    [Annual Review of Animal Biosciences]

    Abstract

    INDUSTRY AND POLICY NEWS

    Affimed Announces 100% Objective Response Rate at Highest Dose in Phase I-II Study of Cord Blood-Derived Natural Killer Cells Pre-Complexed with Innate Cell Engager AFM13 for CD30-Positive Lymphomas

    Affimed N.V. announced interim clinical results from the investigator-initiated Phase I-II study at The University of Texas MD Anderson Cancer Center, evaluating cbNK cells pre-complexed with Affimed’s innate cell engager AFM13.
    [Affimed N.V.]

    Press Release

    FEATURED EVENT

    Gene Regulation: From Emerging Technologies to New Models

    January 23 – 26, 2022
    Santa Fe, New Mexico, United States

    > See All Events

    JOB OPPORTUNITIES

    Research Technician – Hematologic Disorders

    Dana-Farber Cancer Institute – Boston, Massachusetts, United States

    Research Assistant – Translational Research on the Leukemia Niche

    Karolinska Institutet – Flemingsberg, Sweden

    Postdoctoral Position – Drug Resistance

    University Children’s Hospital Zurich – Zurich, Switzerland

    Postdoctoral Position – Gene Editing

    Icahn School of Medicine at Mount Sinai – New York, New York, United States

    Postdoctoral Fellowship – Cell Death

    Duke University – Durham, North Carolina, United States

    > See All Jobs

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