Cord Blood News Volume 13.43 | Dec 02 2021

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    2021-11-02 | CBN 13.43


    Cord Blood News by STEMCELL Technologies
    Vol. 13.43 – 2 December, 2021
    TOP STORY

    Grandmaternal Cells in Cord Blood

    Using human leukocyte antigen-specific quantitative PCR assays on three-generation families, scientists were able to test 28 cord blood samples from healthy primigravid women for grandmaternal maternal microchimerism in whole blood and isolated cells.
    [Ebiomedicine]

    Full Article

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    PUBLICATIONSRanked by the impact factor of the journal

    Increased Proliferation and Differentiation Capacity of Placenta-Derived Mesenchymal Stem Cells from Women of Median Maternal Age Correlates with Telomere Shortening

    Researchers underscored the effect of maternal age on the biological characteristics and stemness properties of placenta-derived mesenchymal stem cells.
    [Aging]

    Full Article

    Human Umbilical Cord Mesenchymal Stem Cells Regulate CD54 and CD105 in Vascular Endothelial Cells and Suppress Inflammation in Kawasaki Disease

    To explore the role of human umbilical cord mesenchymal stem cells (hucMSCs) in inhibiting endothelial inflammation in Kawasaki disease (KD), the effects of hucMSCs on the expression of CD54 and CD105 in endothelial cells in KD were analyzed in vivo and in vitro.
    [Experimental Cell Research]

    Abstract

    Differential Placental CpG Methylation Is Associated with Chronic Lung Disease of Prematurity

    Epigenetic variation in placenta DNA methylation might be associated with differential risk of chronic lung disease, and these associations might be dependent upon sex.
    [Pediatric Research]

    Abstract

    Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Carrying Hsa-miRNA-128-3p Suppress Pancreatic Ductal Cell Carcinoma by Inhibiting Galectin-3

    Researchers investigated the effects of exosomes extracted from human umbilical cord mesenchymal stem cells carrying hsa-miRNA-128-3p on pancreatic cancer cells.
    [Clinical and Translational Oncology]

    Abstract

    The Potential Risk Factors of Placenta Increta and the Role of Octamethylcyclotetrasiloxane

    In vitro, the authors found that octamethylcyclotetrasiloxane could promote the proliferation and migration of HTR8/SVneo cells.
    [Archives of Gynecology and Obstetrics]

    Abstract

    Webinar on Modeling arrhythmias using hPSC-derived cardiomyocytes
    REVIEWS

    Doppler Evaluation of Normal and Abnormal Placenta

    Doppler evaluation of the placenta greatly contributes in the diagnosis and clinical management of placenta accreta, vasa previa, placenta infarctions, infarction hematoma, maternal floor infarction, massive perivillous fibrin deposition, and placenta tumors.
    [Ultrasound in Obstetrics & Gynecology]

    Abstract

    INDUSTRY AND POLICY NEWS

    Rallybio Reports Positive Data in Its Clinical Program for the Prevention of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

    Rallybio Corporation, announced data from its ongoing Phase I/II study of RLYB211, a plasma-derived polyclonal anti-HPA-1a antibody being evaluated for the prevention of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT) showing significant benefit over placebo.
    [Rallybio Corporation (GlobeNewsWire, Inc.)]

    Press Release

    FEATURED EVENT

    Cell Bio Virtual 2021

    December 1 – 10, 2021
    Virtual

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    JOB OPPORTUNITIES

    Postdoctoral Scholar Position – Regeneration

    University of Calgary – Calgary, Alberta, Canada

    Research Technician – Hematologic Disorders

    Dana-Farber Cancer Institute – Boston, Massachusetts, United States

    Research Assistant – Translational Research on the Leukemia Niche

    Karolinska Institutet – Flemingsberg, Sweden

    Postdoctoral Position – Gene Editing

    Icahn School of Medicine at Mount Sinai – New York, New York, United States

    Postdoctoral Fellowship – Cell Death

    Duke University – Durham, North Carolina, United States

    > See All Jobs

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