Cord Blood News Volume 14.07 | Feb 24 2022

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    Justin.choi
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    2022-02-24 | CBN 14.07


    Cord Blood News by STEMCELL Technologies
    Vol. 14.07 – 24 February, 2022
    TOP STORY

    Loss of Slc38a4 Imprinting Is a Major Cause of Mouse Placenta Hyperplasia in Somatic Cell Nuclear Transferred Embryos at Late Gestation

    Researchers showed that placenta hyperplasia of cloned mouse embryos occurred in both middle and late gestation.
    [Cell Reports]

    Full ArticleGraphical Abstract

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    Prenatal Exposure to Triphenyl Phosphate Activated PPARγ in Placental Trophoblasts and Impaired Pregnancy Outcomes

    Using placental trophoblast cell line JEG-3, the authors demonstrated that triphenyl phosphate could induce endoplasmic reticulum stress and cell apoptosis through PPARγ-mediated lipid metabolism.
    [Environmental Pollution]

    AbstractGraphical Abstract

    Exosomal Let-7i-5p from Three-Dimensional Cultured Human Umbilical Cord Mesenchymal Stem Cells Inhibits Fibroblast Activation in Silicosis through Targeting TGFBR1

    Researchers explored whether human umbilical cord MSC-exosomes affected the activation of fibroblasts to alleviate pulmonary fibrosis.
    [Ecotoxicology and Environmental Safety]

    AbstractFull Article

    Gestational Exposure to BDE-209 Induces Placental Injury via the Endoplasmic Reticulum Stress-Mediated PERK/ATF4/CHOP Signaling Pathway

    Scientists examined the impacts of gestational exposure to BDE-209, the most abundant polybrominated diphenyl ether conger detected in human samples, on placental structure and function, and its model of action in vivo and in vitro.
    [Ecotoxicology and Environmental Safety]

    Full Article

    Umbilical Cord Blood Leptin and IL-6 in the Presence of Maternal Diabetes or Chorioamnionitis

    Cord blood samples were obtained from 104 term infants, including 47 exposed to maternal diabetes. Leptin, insulin, and IL-6 were quantified by multiplex assay.
    [Frontiers in Endocrinology]

    Full Article

    Differential Expression Profiling of microRNAs in Human Placenta-Derived Mesenchymal Stem Cells Cocultured with Grooved Porous Hydroxyapatite Scaffolds

    Researchers analyzed the contribution of hydroxyapatite scaffold to the osteogenic differentiation of human placenta-derived MSC from the perspective of miRNA differential expression.
    [DNA and Cell Biology]

    Abstract

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    REVIEWS

    Cerebral Palsy and the Placenta: A Review of the Maternal-Placental-Fetal Origins of Cerebral Palsy

    The authors narratively review clinical studies reporting associations between prenatal and perinatal environmental factors and the risk of developing cerebral palsy.
    [Experimental Neurology]

    Abstract

    Application of Cell Free DNA in ART

    Scientists highlight the cell free DNA biomarker might constitute a supplemental tool for improving in vitro fertilization and pregnancy outcomes, female infertility management.
    [Placenta]

    Abstract

    INDUSTRY AND POLICY NEWS

    IMAC Holdings, Inc. Announces Completion of Second Cohort of Its Phase I Clinical Study of Umbilical Cord-Derived Mesenchymal Stem Cells for the Treatment of Bradykinesia Due to Parkinson’s Disease

    IMAC Holdings, Inc. announced that it has completed the second cohort of its Phase I clinical trial for its investigational compound utilizing umbilical cord-derived allogenic MSC for the treatment of bradykinesia due to Parkinson’s disease.
    [IMAC Holdings, Inc.]

    Press Release

    FEATURED EVENT

    The 37th Annual Congress of the European Association of Urology – Amsterdam

    March 18 – March 21
    Virtual

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    JOB OPPORTUNITIES

    Faculty Position – Hematopathology

    University of Vermont – Burlington, Vermont, United States

    Postdoctoral Associate – Cell Viability

    Singapore-MIT Alliance for Research and Technology (SMART) Centre – Singapore, Singapore

    Postdoctoral Research Fellow – Virology

    George Mason University – Prince William, Virginia, United States

    Postdoctoral Position – Regenerative Medicine

    Stanford University – Stanford, California, United States

    Postdoctoral Scholar – Pediatric Hematology

    Penn State College of Medicine – Hershey, Pennsylvania, United States

    > See All Jobs

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