Cord Blood News Volume 14.08 | Mar 3 2022

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    Justin.choi
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    114






    2022-03-03 | CBN 14.08


    Cord Blood News by STEMCELL Technologies
    Vol. 14.08 – 3 March, 2022
    TOP STORY

    Dichotomy in Hypoxia-Induced Mitochondrial Fission in Placental Mesenchymal Cells during Development and Preeclampsia: Consequences for Trophoblast Mitochondrial Homeostasis

    The authors investigated the impact of oxygen on mitochondrial dynamics in placental MSCs that were vital for proper placental development.
    [Cell Death & Disease]

    Full Article

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    PUBLICATIONSRanked by the impact factor of the journal

    Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Loaded with miR-223 Ameliorate Myocardial Infarction through P53/S100A9 Axis

    Scientists explored the mechanism of human umbilical cord  MSC-derived extracellular vesicles loaded with miR-223 on myocardial infarction. Inflammation, cell biological functions, and fibrosis in vitro were measured.
    [Genomics]

    Abstract

    Coexistence of HLA and KIR Ligand Mismatches as a Risk Factor for Viral Infection Early after Cord Blood Transplantation

    The authors conducted a retrospective multicenter study to assess the effect of human leukocyte antigen and killer immunoglobulin-like receptor ligand mismatches on viral infections after cord blood transplantation.
    [Bone Marrow Transplantation]

    Abstract

    Sex-Specific Effects of Bisphenol A on the Signaling Pathway of ESRRG in the Human Placenta

    Researchers explored whether expression of estrogen-related receptor gamma (ESRRG) signaling mediated BPA-induced placental dysfunction, and determined whether changes in the ESRRG signaling pathway were sex-specific.
    [Biology of Reproduction]

    Abstract

    Gardnerella vaginalis Infection in Pregnancy: Effects on Placental Development and Neonatal Outcomes

    Scientists investigated the effects of Gardnerella vaginalis infection on the placenta, particularly with regards to the syncytiotrophoblasts and vascular development, and related these to neonatal outcomes.
    [Placenta]

    Abstract

    Development of Dynamic Image Analysis Methods to Measure Vascularisation and Syncytial Nuclear Aggregates in Human Placenta

    Placenta samples were stained for endothelial cells and syncytial nuclear aggregates and analyzed in Qupath software.
    [Placenta]

    AbstractGraphical Abstract

    Immunomodulatory Effect of Epidermal Growth Factor Secreted by Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Atopic Dermatitis

    Scientists investigated the immunomodulatory effect of epidermal growth factor (EGF) secreted by hUCB-MSCs on atopic dermatitis.
    [International Journal of Stem Cells]

    Abstract

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    REVIEWS

    Developments in Functional Imaging of the Placenta

    The authors review emerging imaging technology being used to measure the function of the placenta and new developments in the computational analysis of this data.
    [British Journal of Radiology]

    Abstract

    INDUSTRY AND POLICY NEWS

    The OPTI-STEM Consortium Led by CDMO Cell-Easy Receives €7M from the French Government and Bpifrance and €800,000 from the Occitanie Region to Democratize Access to Cell Therapy in France and Europe

    The R&D consortium led by contract development and manufacturing organization Cell-Easy has obtained public funding of more than €7 million as part of the “Biotherapies and Bioproduction of Innovative Therapies” acceleration strategy, operated on behalf of the French government by Bpifrance.
    [BusinessWire, Inc.]

    Press Release

    FEATURED EVENT

    Sy-Stem 2022

    March 20 – March 25
    Vienna, Austria

    > See All Events

    JOB OPPORTUNITIES

    Postdoctoral Fellow – Hematopoietic Cells

    UT Southwestern Medical Center – Dallas, Texas, United States

    Faculty Position – Hematopathology

    University of Vermont – Burlington, Vermont, United States

    Postdoctoral Associate – Cell Viability

    Singapore-MIT Alliance for Research and Technology (SMART) Centre – Singapore, Singapore

    Postdoctoral Research Fellow – Virology

    George Mason University – Prince William, Virginia, United States

    Postdoctoral Position – Regenerative Medicine

    Stanford University – Stanford, California, United States

    > See All Jobs

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