Cord Blood News Volume 14.13 | Apr 7 2022

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    2022-04-07 | CBN 14.13


    Cord Blood News by STEMCELL Technologies
    Vol. 14.13 – 7 April, 2022
    TOP STORY

    Absence of SARS-CoV-2 Spike Glycoprotein Expression in Placentas from Individuals after mRNA SARS-CoV-2 Vaccination

    The authors identified 48 patients receiving one or two doses of mRNA SARS-CoV-2 vaccine during gestation and used immunohistochemistry against SARS-CoV-2 Spike protein in formalin-fixed, paraffin-embedded placental tissue.
    [Modern Pathology]

    Full Article


    Dr. Daniel Dever, describes a CRISPR-Cas9-based protocol for gene editing hematopoietic stem cells in this on-demand webinar.
    PUBLICATIONSRanked by the impact factor of the journal

    Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Relieves Diabetic Retinopathy through a microRNA-30c-5p-Dependent Mechanism

    Scientists attempted to unveil the role of delivery of miR-30c-5p by human umbilical cord MSC-derived extracellular vesicles in diabetic retinopathy.
    [Diabetes Research and Clinical Practice]

    Abstract

    Single-Cell Transcriptional Diversity of Neonatal Umbilical Cord Blood Immune Cells Reveals Neonatal Immune Tolerance

    Researchers applied single-cell RNA sequencing and single-cell sequencing assay for transposase-accessible chromatin to systematically profile umbilical cord blood nucleated cells and peripheral blood mononuclear cells to identify their composition and differentially expressed genes.
    [Biochemical and Biophysical Research Communications]

    Full Article

    Hyperacute Transplantation of Umbilical Cord Mesenchymal Stromal Cells in a Model of Severe Intracerebral Hemorrhage

    Wistar rats were randomly selected to receive an intravenous injection of human umbilical cord-MSC or the vehicle one hour after a severe Intracerebral hemorrhage.
    [Future Science OA]

    Full Article

    Transplantation of Umbilical Cord Blood-Derived Mesenchymal Stem Cells as Therapy for Adriamycin Induced-Cardiomyopathy

    Scientists studied the therapeutic effects of umbilical cord blood-derived MSCs transplantation on adriamycin-induced cardiomyopathy.
    [Bioengineered]

    Full ArticleGraphical Abstract

    Maternal Metabolizable Protein Restriction during Gestation Affects the Vascular Function of Maternal and Fetal Placental Arteries in Sheep

    In vitro dose-response curves to bradykinin, sodium nitroprusside, potassium chloride, and phenylephrine in caruncular and cotyledonary arteries were performed.
    [theriogenology]

    Full Article

    Resources for Your T Cell Therapy Research
    REVIEWS

    The Therapeutic Potential of Stem Cell-Derived Exosomes in the Ulcerative Colitis and Colorectal Cancer

    The authors review the recent research advances of therapies based on the MSC-exo for treating ulcerative colitis and colorectal cancer.
    [Stem Cell Research & Therapy]

    Full Article

    INDUSTRY AND POLICY NEWS

    Elysium Healthâ„¢ Announces New Research Initiative in Partnership with the University of Oxford in Connection with the Landmark INTERBIO-21st Study

    Elysium Health, Inc.â„¢ has entered into a material transfer agreement with the University of Oxford to analyze the DNA methylation patterns of 2,500 umbilical cord blood samples from the landmark INTERBIO-21st study with the aim of developing novel, non-invasive, and accessible measures to help assess the risk of growth and neurodevelopment delay in early childhood.
    [Elysium Healthâ„¢ (BioSpace, Inc.)]

    Press Release

    FEATURED EVENT

    ISCT 2022 San Francisco Annual Meeting

    May 4 – May 7, 2022
    San Francisco, California, United States

    > See All Events

    JOB OPPORTUNITIES

    Postdoctoral Research Associate – Pharmaceutical Sciences

    St. Jude Children’s Research Hospital – Memphis, Texas, United States

    Postdoctoral Fellow Position – Translational Research

    Stanford University – Stanford, California, United States

    Postdoctoral Positions – Epigenetics of Stem Cells, Development and Cancer

    Albert Einstein College of Medicine – Bronx, New York, United States

    Faculty Position – Tissue Engineering

    Mayo Clinic – Jacksonville, Florida, United States

    Principal Scientific Researcher – Cell and Tissue Genomics

    Genentech, Inc. – South San Francisco, California, United States

    > See All Jobs

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