 | | Vol. 14.15 – 21 April, 2022 |
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| The authors employed the naive-to-primed transition of human pluripotent stem cells to model peri-implantation epiblast development.
[Cell Stem Cell] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| The effect of SARS-CoV-2 infection on placental function is not well understood. Analysis of placentas from women who tested positive at delivery showed SARS-CoV-2 genomic and subgenomic RNA in 22 out of 52 placentas.
[iScience] |
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| Researchers identified the suppressing roles of exosomal miR-15a-5p from umbilical cord MSCs in the epithelial-mesenchymal transition and metastasis of cholangiocarcinoma.
[Cell Death Discovery] |
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| Western blotting observed that carboxyl terminus of heat shock protein 70 interacting protein (CHIP)-overexpressing Wharton’s jelly-derived MSCs could rescue nerve damage observed in streptozotocin-induced diabetic rats by activating the AMPKα/AKT and PGC1α/SIRT1 signaling pathway.
[Environmental Toxicology] |
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| The authors attempted to decrease the false-positive rate of non-invasive prenatal testing using cell-free fetal DNA (cffDNA) fraction enrichment and the SCPMP mosaicism proportion threshold application via cffDNA quantification.
[Prenatal Diagnosis] |
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| Researchers assessed the effect of human umbilical cord blood MSCs transplantation on schistosomal hepatic fibrosis in mice.
[Pathogens and Global Health] |
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| Natural killer (NK) cells were isolated from human peripheral blood mononuclear cells and human cord blood, and were expanded and activated using a cytokine cocktail.
[Pediatric Blood & Cancer] |
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| Investigators explore what is known regarding the mechanisms by which environmental exposures can impact early intrauterine development and thus result in adverse outcomes in the immediate, short, and long term.
[Seminars in Cell & Developmental Biology] |
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| Scientists summarize the role and regulation of granulocyte colony-stimulating factor (G-CSF) in normal pregnancy and reproductive-related disease, and the clinical applications of G-CSF in patients undergoing in vitro fertilization with thin endometrium and repeated implantation failure.
[Biomedicine & Pharmacotherapy] |
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| Scientists at Cedars-Sinai are launching their expertise into space to see if they can elevate the next generation of stem cell and gene therapies by harnessing the near-zero gravity conditions of spaceflight.
[Cedars Sinai] |
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| May 11 – 15, 2022
Amsterdam, The Netherlands |
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| | University of Gothenburg – Gothenburg, Sweden |
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| European Molecular Biology Laboratory – Barcelona, Spain |
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| | Novo Nordisk – Fremont, California, United States |
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| St. Jude Children’s Research Hospital – Memphis, Texas, United States |
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| | Stanford University – Stanford, California, United States |
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