Cord Blood News Volume 2.33 | Sep 2 2010

Isolation and Killing of Candidate Chronic Myeloid Leukemia Stem Cells by Antibody Targeting of IL-1 Receptor Accessory Protein
Here researchers used gene-expression profiling to identify IL-1 receptor accessory protein as up-regulated in chronic myeloid leukemia CD34+ cells and also in cord blood CD34+ cells as a consequence of retroviral BCR/ABL1 expression. [Proc Natl Acad Sci USA]

		Need to expand CD34+ cells? StemSpan® serum-free expansion media are optimized for expanding hematopoietic stem and progenitor cells
		DOWNLOAD THE TECHNICAL BULLETIN

Complimentary Webinar Presented by STEMCELL Technologies: EPO and Erythropoiesis, Detecting Lineage Commitment

Prospective Evaluation of Allogeneic Hematopoietic Stem-Cell Transplantation From Matched Related and Matched Unrelated Donors in Younger Adults With High-Risk Acute Myeloid Leukemia: German-Austrian Trial AMLHD98A
The purpose of this study is to assess the impact of allogeneic hematopoietic stem-cell transplantation from matched related donors and matched unrelated donors on outcome in high-risk patients with acute myeloid leukemia within a prospective multicenter treatment trial. [J Clin Oncol]

Human Umbilical Cord Blood–Derived Endothelial Cells Reendothelialize Vein Grafts and Prevent Thrombosis
The objective of this study was to accelerate vein graft endothelialization and reduce vein graft thrombosis with human umbilical cord blood–derived endothelial cells because loss of endothelium contributes to vein graft thrombosis and neointimal hyperplasia. [Arterioscler Thromb Vasc Biol]

DLK-1 as a Marker to Distinguish Unrestricted Somatic Stem Cells and Mesenchymal Stromal Cells in Cord Blood
Here scientists demonstrate that the expression of genes and the differentiation toward the adipogenic lineage can discriminate between cord blood mesenchymal stromal cells and unrestricted somatic stem cells. [Stem Cells Dev]

Therapeutic Effects of Umbilical Cord Blood-Derived Mesenchymal Stem Cell Transplantation in Experimental Lupus Nephritis
Researchers investigated whether human umbilical cord blood-derived mesenchymal stem cells transplantation is useful in alleviating lupus nephritis in a murine model. [Cell Transplant]

Acquisition of G0 State by CD34-Positive Cord Blood Cells After Bone Marrow Transplantation
Behavioral changes of hematopoietic stem cells in their cell cycle and oxygenation state during and after bone marrow engraftment may provide insights into hematopoietic stem cell regulation, mediating the improvement of clinical hematopoietic stem cell transplantation protocols and the eradication of leukemia stem cells. [Exp Hematol]

Stem Cell-Like Properties of Human Umbilical Cord Lining Epithelial Cells and the Potential for Epidermal Reconstitution
Investigators are currently looking at the potential of human umbilical cord lining cells as a source of epithelial stem cells with appropriate differentiation capacity for potential epidermal reconstitution. [Cytotherapy]

		Further Improve Hematopoietic Progenitor Proliferation with Human LDL by STEMCELL Technologies
		ORDER NOW

Cord Blood America Offers $50,000 Guarantee That Stem Cells It Stores Will Engraft in Transplant Procedure
Cord Blood America, Inc. announced a $50,000 Quality Service Guarantee. [Cord Blood America, Inc. Press Release]

Cord Blood America CEO Updates Investors on Financial Developments and Stem Cell News in Interview
Cord Blood America, Inc. announced that CEO Matt Schissler was interviewed recently by Tom Allinder of InBoundMarketingPR. [Cord Blood America, Inc. Press Release]

Cryo-Save Group Half Year Results 2010
Cryo-Save Group N.V. has published its interim results for the six months ended 30 June 2010. [Cryo-Save Group N.V. Press Release]

Thermogenesis Announces Sale of BioArchive Systems in Asia as Company Increases Presence in Key Market
ThermoGenesis Corp. said it has sold two BioArchive® Systems to HealthBanks Biotech Company, Ltd. [Thermogenesis Corp. Press Release]

Pluristem’s Placenta Derived Cells Chosen by European Commission’s Seventh Framework Program Study for Treatment of Diastolic Heart Failure (DHF) in Type 2 Diabetic Patients
Pluristem Therapeutics Inc. announced that its PLX cell therapy product was selected as the only cell therapy product candidate to enter into a study seeking treatments for diastolic heart failure in the European Commission’s Seventh Framework Program. [Pluristem Therapeutics Press Release]

Health Bank Appoints Top US Scientist as Director
Virgin Health Bank has appointed a top American cord blood banking and cellular therapy scientist as director of operations. [Gulf Times Press Release]

NIH Orders Immediate Shutdown of Intramural Human Embryonic Stem Cell Research
Responding to a court order, the National Institutes of Health (NIH) ordered intramural researchers studying human embryonic stem cells to shut down their experiments. [National Institutes of Health, United States]

Obama Administration Appeals Stem Cell Injunction
The Obama administration appealed a ruling that blocked federal funding of embryonic stem cell research and asked the judge who issued the injunction to put it on hold pending the appeal. [Obama Administration, United States]

NIH Asks Judge to Suspend Stem Cell Research Injunction
Warning of a “devastating impact” on ongoing research, the National Institutes of Health (NIH) asked a federal court to stay a preliminary injunction that last week forced NIH to suspend future grant payments to study human embryonic stem cells (hESC) and shut down its in-house research on hESCs. [National Institutes of Health, United States]

NIH Director’s Response to Stem Cell Injunction [National Institutes of Health, United States]

National Center for Research Resources; Notice of Closed Meeting (FR Doc. 2010-21280) [National Institutes of Health, United States]

National Cancer Institute’s Best Practices for Biospecimen Resources (FR Doc. 2010-20872) [National Institutes of Health, United States]

Revolutionary Genome Sequencing Technologies — The $1000 Genome (SBIR [R43/R44]) (RFA-HG-10-014) [National Institutes of Health, United States]

National Heart, Lung, and Blood Institute; Notice of Closed Meeting [FR Doc. 2010-20857] [National Institutes of Health, United States]

National Heart, Lung, and Blood Institute; Notice of Closed Meeting [FR Doc. 202010-21526] [National Institutes of Health, United States]

Food and Drug Administration Clinical Trial Requirements, Regulations, Compliance, and Good Clinical Practice; Public Workshop [FR Doc. 2010-20834] [Food and Drug Administration, United States]

Select Biosciences 5th Annual Stem Cells World Congress
January 24-25, 2011
San Diego, United States

Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community.

Visit here to post your career opportunities.

Have we missed an important article or publication in Cord Blood News? Click here to submit!

Comments or Suggestions? Email info@connexoncreative.com with your feedback.