SCIENCE NEWS
Umbilical Cord Cells May Treat Arthritis, Studies Suggest
Umbilical cord stem cells may be useful in the treatment of rheumatoid arthritis. Animal and in vitro experiments have shown that mesenchymal stem cells taken from umbilical cord blood can suppress inflammation and attenuate collagen-induced arthritis. [Press release from EurekAlert! discussing online prepublication in Arthritis Research and Therapy]
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CURRENT PUBLICATIONS (Ranked by Impact Factor of the Journal)
Outcomes After Related and Unrelated Umbilical Cord Blood Transplantation for Non-Fanconi Hereditary Bone Marrow Failure
In patients with hereditary bone marrow failure syndromes, related umbilical cord blood transplant is associated with excellent outcomes while in unrelated umbilical cord blood transplant increasing cell dose and better HLA matching might provide better results. [Haematologica]
Therapeutic Potential of Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Rheumatoid Arthritis
Human umbilical cord (UC)-mesenchymal stem cells (MSCs) suppressed the various inflammatory effects of fibroblast-like synoviocytes and T cells of rheumatoid arthritis in vitro, and attenuated the development of collagen-induced arthritis in vivo, strongly suggesting that UC-MSCs might be a therapeutic strategy in rheumatoid arthritis. [Arth Res Ther]
Intravenous Human Umbilical Cord Blood Transplantation for Stroke: Impact on Infarct Volume and Caspase-3-Dependent Cell Death in Spontaneously Hypertensive Rats
Researchers aimed to evaluate the potential neuroprotective effects produced by human umbilical cord blood cells in terms of reduced infarct volume and caspase-3-dependent cell death. [Exp Neurol]
Hematopoietic Stem Cell Transplantation Does Not Retard Disease Progression in the Psycho-Cognitive Variant of Late-Onset Metachromatic Leukodystrophy
Researchers report detailed clinical and neuropsychological assessments after hematopoietic stem-cell transplantation in a patient with a late-onset psycho-cognitive form of metachromatic leukodystrophy. [J Inherit Metab Dis]
Differential Survival of AML Subpopulations in NOD/SCID Mice
Bone marrow cells from patients with acute myeloid leukemia (AML) were separated according to CD34 expression, aldehydehydrogenase activity and divisional kinetics in comparison to cord blood-derived CD34+ hematopoietic stem cells, evaluating survival and expansion in NOD/SCID mice. [Exp Hematol]
Polychromatic Flow Cytometry Analysis of CD34+ Hematopoietic Stem Cells in Cryopreserved Early Preterm Human Cord Blood Samples
Results evidence the hematopoietic peculiarity of human early preterm cord blood, potentially useful for highlighting early steps of human hematolymphopoiesis as well as for developing novel strategies of stem cell-based therapy. [Cytometry A]
Schwann Cell-Like Remyelination Following Transplantation of Human Umbilical Cord Blood (hUCB)-Derived Mesenchymal Stem Cells in Dogs with Acute Spinal Cord Injury
Researchers conducted preliminary investigations on the remyelination of injured spinal cords with hUCB-mesenchymal stem cell transplantations and observed its long term effects on dogs with spinal cord injury. [Journal Neurol Sci]
Hematopoietic Stem Cell Transplantation in Severe Congenital Neutropenia
Since 2004, eight hematopoietic stem cell transplantations were performed in seven patients. Three grafts were from HLA-identical siblings, three from matched unrelated donors and two were cord blood units. [Pediatr Blood Cancer]
Relationship Between Radiosensitivity of Human Neonatal Hematopoietic Stem/Progenitor Cells and Individual Maternal/Neonatal Obstetric Factors
The study investigated the potential relationship between the radiosensitivity of hematopoietic stem/progenitor cells in placental/umbilical cord blood, which was obtained from singleton and full-term deliveries, and maternal/neonatal obstetric factors. [J Radiat Res]
Enhanced Osteogenic Differentiation of Cord Blood-Derived Unrestricted Somatic Stem Cells on Electrospun Nanofibers
Observations suggested the enhanced proliferation and osteogenic differentiation of cord blood-derived unrestricted somatic stem cells on poly-L-lactide-collagen nanofiber scaffolds and introduced a new combination of stem cell-scaffold constructs with desired characteristics for application in bone tissue engineering. [J Mater Sci Mater Med]
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INDUSTRY NEWS
Cord Blood America Becomes Alliance Partner of National Association Representing U.S. Health Insurance Plans
Cord Blood America, Inc. announced that it is the first cord blood stem cell storage company to become an alliance partner of AHIP (America’s Health Insurance Plans). [Cord Blood America, Inc. Press Release]
Potential Blood Center Merger
Three of Florida’s largest independent, not-for-profit blood banks, Community Blood Centers of Florida, Florida’s Blood Centers and Florida Blood Services announced that they have received approval from each of their boards of directors to explore the option of merging into one organization. [Florida’s Blood Center Press Release]
St. Louis Cord Blood Bank Wins $1.4 Million Grant
The St. Louis Cord Blood Bank received a three-year, $1.4 million federal grant. The contract from the Office of Health Resources and Services Administration within the U.S. Department of Health and Human Services is for collection and maintenance of genetically diverse umbilical cord blood units, especially those from minority parents, the blood bank said. [St. Louis Business Journal]
StemCyte Awarded $488,950 for Advanced Therapeutic Applications of Umbilical Cord Blood Stem Cells from the Qualifying Therapeutic Discovery Project
StemCyte, Inc. announced that the Company has been awarded two cash grants totaling $488,950 under the U.S. Internal Revenue Service’s Qualifying Therapeutic Discovery Project program. [PR Newswire]
China Cord Blood Corporation Commences Warrant Exchange Offer
China Cord Blood Corporation commenced its previously announced warrant exchange offer, and provided warrant holders with participation details. [China Cord Blood Corporation Press Release]
NeoStem Announces Pricing of Concurrent Offerings for $19 Million in Gross Proceeds
NeoStem, Inc., an international biopharmaceutical company with product and service revenues, global research and development capabilities and operations in three distinct business units, U.S. adult stem cells, China adult stem cells, and China pharmaceuticals announced the pricing of concurrent offerings. [NeoStem, Inc. Press Release]
Stem Cells Journal Awards Human Cord-Blood Research
The journal Stem Cells has announced Dr. Cinzia Rota as the winner of the annual Stem Cells Young Investigator Award. Dr. Rota, from the Mario Negri Institute for Pharmacological Research in Bergamo, Italy, was awarded the prize for her paper entitled ‘Life-Sparing Effect of Human Cord Blood-Mesenchymal Stem Cells in Experimental Acute Kidney Injury.’ [EurekAlert!]
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EVENTS (Listed by Date)
Stem Cell Network’s 10th Annual Scientific Meeting
November 22-24, 2010
Calgary, Canada
52nd American Society of Hematology (ASH) Annual Meeting and Exposition
December 4-7, 2010
Orlando, United States
Pharmacology in Stem Cells Research and Regenerative Medicine
December 17, 2010
London, United Kingdom
NEW The 3rd Guangzhou International Conference on Stem Cell Biology and Regenerative Medicine
December 17-19, 2010
Guangzhou, China
5th Annual Stem Cells and Regenerative Medicine World Congress
January 24-25, 2011
San Diego, United States
IQPC’s 4th Biobanking Conference
January 24-26, 2011
Philadelphia, United States
NEW Stem Cell Research Forum of India 2nd Annual Meeting
February 8-11, 2011
Bangalore, India
BMT Tandem Meetings (ASBMT/CIBMTR)
February 17-21, 2011
Honolulu, Hawaii
1st Annual Clinical Meeting of the Cell Society
February 18-19, 2011
La Jolla, United States
NEW Stem Cells 2011 – Innovation & Commercialisation
February 23-24, 2011
London, United Kingdom
Molecular Medicine Tri-Conference: Stem Cells – Revolutionizing Regenerative Medicine and Personalized Therapy 2011
February 23-25, 2011
San Francisco, United States
6th Annual Stem Cell Summit
March 1, 2011
New York, United States
American Association for Cancer Research (AACR) Stem Cells, Development, and Cancer
March 3-6, 2011
Vancouver, Canada
NEW 15th Annual Hilton Head Workshop – Regenerative Medicine, Innovations for Clinical Applications
March 16-19, 2011
Hilton Head Island, United States
NEW StemCONN 11
March 22, 2011
Farmington, United States
Keystone Symposia: Hematopoiesis
March 27-April 1, 2011
Big Sky, United States
United Kingdom National Stem Cell Network 2011 Annual Scientific Conference
March 30-April 1, 2011
York, United Kingdom
American Association for Cancer Research (AACR) 102nd Annual Meeting 2011
April 2-6, 2011
Orlando, United States
Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community.
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