National Cord Blood Bank to Recruit Ethnic Donors Aggressively Canada’s new national cord blood bank plans to aggressively recruit donors who represent the country’s diverse ethnic and multi-ethnic mix so as to increase the odds of ultimately providing stem cell matches to treat cancer patients with conditions such as leukemia and lymphoma. [CMAJ] Defective Neuromuscular Transmission in the SOD1G93A Transgenic Mouse Improves After Administration of Human Umbilical Cord Blood Cells To assess the effect of human umbilical cord blood (hUCB) transplantation on neuromuscular transmission in SOD1G93A transgenic mice, researchers studied the probability of neuromuscular transmission (PNMT) in 3 SOD1G93A mice transplanted with hUCB and compared to PNMT in 4 SOD1G93A mice without cell transplantation and 3 non-mutant SOD1 transgenic mice. [Stem Cell Rev] New Simple and Rapid Method for Purification of Mesenchymal Stem Cells from the Human Umbilical Cord Wharton Jelly Researchers have developed a simple and rapid method for isolation of human umbilical cord matrix stem cells. [Tissue Eng Part A] Mycophenolate and Tacrolimus for Graft-Versus-Host Disease Prophylaxis for Elderly After Cord Blood Transplantation: A Matched Pair Comparison With Tacrolimus Alone Researchers conducted a single institute pilot study assessing the safety and effectiveness of mycophenolate mofetil (MMF) and tacrolimus (FK) combination as a graft-versus-host disease (GVHD) prophylaxis for 29 patients (FK+MMF), and the results were compared with matched-pairs extracted from a historical database who received FK alone as GVHD prophylaxis (control). [Transplantation] Biomechanical Effects of Flow and Coculture on Human Aortic and Cord Blood-Derived Endothelial Cells The objective of this study was to quantify the elastic modulus of human endothelial cells derived from umbilical cord blood cocultured with smooth muscle cells under static and flow conditions using atomic force microscopy. [J Biomech] Allogeneic Hematopoietic Transplantation Using Haploidentical Donor vs. Unrelated Cord Blood Donor in Pediatric Patients: A Single-Center Retrospective Study Researchers retrospectively analyzed outcomes in 67 children with acute leukemia who received hematopoietic stem cell transplantation from alternative allogeneic donors: 29 received a haploidentical family donor and 38, an unrelated cord blood donor. [Eur J Haematol] Osteogenic Differentiation of GFP-Labeled Human Umbilical Cord Blood Derived Mesenchymal Stem Cells After Cryopreservation The aim of this study was to determine the effect of cryopreservation on the osteogenic differentiation of green fluorescent protein (GFP)-marked umbilical cord blood derived mesenchymal stem cells in vitro. [Cryobiology] |