Umbilical Cord Mesenchymal Stromal Cell with Autologous Bone Marrow Cell Transplantation in Established Type 1 Diabetes: A Pilot Randomized Controlled Open-Label Clinical Study to Assess Safety and Impact on Insulin Secretion Scientists determined the safety and effects on insulin secretion of umbilical cord mesenchymal stromal cells plus autologous bone marrow mononuclear cell stem cell transplantation without immunotherapy in established type 1 diabetes. [Diabetes Care] Abstract Investigating the Potential of Human Placental Derived Extracellular Matrix Sponges Coupled with Amniotic Membrane-Derived Stem Cells for Osteochondral Tissue Engineering Scientists fabricated human placental derived extracellular matrix sponges (PEMS) for repair of osteochondral tissue through a decellularization process. In vitro, PEMS provided a non-cytotoxic and bioactive cues rich environment for the human amniotic membrane derived stem cells to proliferate and differentiate into chondrogenic and osteogenic lineage under induction. [J Mater Chem B] Abstract Placenta Mesenchymal Stem Cell Derived Exosomes Confer Plasticity on Fibroblasts The authors isolated human placenta mesenchymal stem cell-derived exosomes and examined their function in vitro. [J Cell Biochem] Abstract Mast Cells Release Chemokine CCL2 in Response to Parkinsonian Toxin 1-Methyl-4-Phenyl-Pyridinium (MPP+) Investigators analyzed if MPP+ activates mouse and human mast cells to release chemokine (C-C motif) ligand 2 (CCL2). Mouse bone marrow-derived mast cells and human umbilical cord blood-derived cultured mast cells were incubated with MPP+ for 24 hours and CCL2 levels were measured in the supernatant media by ELISA. [Neurochem Res] Abstract Inverse Association between Maternal 25OHD Level and Cord GLP-1/GIP Concentrations Scientists explored whether maternal 25-hydroxyvitamin D levels in normal pregnancy have association with diabetes-related hormone levels and glycated albumin. A prospective cohort study was performed to collect serum samples from 612 pairs of pregnant women and cord blood of their offspring. [Pediatr Res] Abstract Isolation and Morphological Characterization of Ovine Amniotic Fluid Mesenchymal Stem Cells Researchers obtained mesenchymal stem cells from ovine amniotic fluid and determined the expansion capacity, surface and intracellular marker expression, karyotype, and multilineage differentiation ability of these ovine amniotic fluid mesenchymal stem cells. [Exp Anim] Abstract |