Outcomes of Unrelated Cord Blood Transplantation in Patients with Multiple Myeloma: A Survey on Behalf of Eurocord, the Cord Blood Committee of Cellular Therapy and Immunobiology Working Party, and the Chronic Leukemia Working Party of the European Society for Blood and Marrow Transplantation The authors retrospectively analyzed 95 patients, 85 with multiple myeloma and 10 with plasma cell leukemia, receiving single or double umbilical cord blood transplantation from 2001 to 2013. [Haematologica] Abstract Low Oxygen Tension Reveals Distinct HOX Codes in Human Cord Blood-Derived Stromal Cells Associated with Specific Endochondral Ossification Capacities In Vitro and In Vivo The expression of 39 human HOX genes was determined in neonatal cord blood stromal cells and linked to differentiation-associated signatures. In cord blood, unrestricted somatic stromal cells, lacking HOX gene expression, and cord blood-derived multipotent stromal cells, expressing about 20 HOX genes, are distinguished by their specific HOX code. [J Tissue Eng Regen Med] Abstract Brentuximab Vedotin in Combination with or without Donor Lymphocyte Infusion for Patients with Hodgkin Lymphoma after Allogeneic Stem Cell Transplantation Researchers evaluated the safety and efficacy of Brentuximab vedotin with or without the addition of donor lymphocyte infusion after allogeneic stem cell transplantation in 16 patients with advanced Hodgkin lymphoma. [Bone Marrow Transplant] Abstract Changing Trends of Unrelated Umbilical Cord Blood Transplantation (UCBT) for Hematological Diseases in Patients Older Than 50 Years: An Eurocord – CIBMTR Survey Scientists conducted a registry-based survey to evaluate the use of umbilical cord blood transplantation in patients aged 50 years and older, both in Europe and North America. [Biol Blood Marrow Transplant] Abstract Atomized Human Amniotic Mesenchymal Stromal Cells for Direct Delivery to the Airway for Treatment of Lung Injury Researchers demonstrated that human amniotic mesenchymal stromal cells are able to survive after being sprayed onto substrates with different stiffness, especially in the presence of collagen I. [J Aerosol Med Pulm Drug Deliv] Abstract Hepatitis B Virus Replication in CD34+ Hematopoietic Stem Cells From Umbilical Cord Blood The susceptibility of CD34+ hematopoietic stem cells (HSCs) to hepatitis B virus (HBV) was investigated. Cord blood-derived CD34+ HSCs were exposed to HBV in vitro, and immunocytochemistry, transmission electron microscopy, and RT-PCR were used to identify viral-related proteins and specific viral genomic sequences. [Med Sci Monit] Abstract |