 | | Vol. 10.00 – 8 January, 2024 |
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| Targeting TCF4 genetically or pharmacologically, using a bromodomain inhibitor, increased immunogenicity and sensitivity of mesenchymal-like cells to immune checkpoint blockade and targeted therapy.
[Cell] |
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| PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
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| Scientists introduced a fully-implantable wireless-powered tactile sensory system embedded in artificial skin, with stable operation, to restore permanently damaged tactile function and promote wound healing for regenerating severely damaged skin.
[Nature Communications] |
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| Investigators used single-cell RNA sequencing to provide a map of the cellular dynamics during early inflammation in mouse skin wounds.
[eLife] |
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| Scientists developed glycidyl methacrylate-modified human-derived gelatin hydrogels for use in tissue engineering applications.
[Biomacromolecules] |
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| Researchers cultured hair follicle (HF)-derived cells, which were mainly composed of HF stem cells, in the form of 3D spheroids using a microwell array, and investigated the influences of microwell depth on HF spheroid formation and biological conditions.
[Scientific Reports] |
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| The authors developed a novel biomaterial, the human keratin matrix, which was characterized, and tested in vitro and in vivo.
[Wound Repair And Regeneration] |
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| Since the connection between cells and matrix was provided by transmembrane integrin receptors, scientists aimed at studying the dynamics of signaling pathways associated with integrins on an in vitro model of wound healing using human skin fibroblasts.
[Applied Biochemistry And Biotechnology] |
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| Signal peptides-engineered etanercept/TNF-α inhibitor proteins demonstrated therapeutic efficacy in an imiquimod-induced psoriasis model by reducing hyperkeratosis and inflammation.
[Proceedings Of The National Academy Of Sciences Of The United States Of America] |
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| Using multiple PLK1-modulated melanoma cell lines, investigators found that PLK1 was involved in the regulation of cell migration, invasion, and epithelial-mesenchymal transition via its kinase activity and NOTCH activation.
[NPJ Precision Oncology] |
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| The authors review the state of the microbiota field in the context of melanoma, the recent breakthroughs in defining microbial modes of action, and how to modulate the microbiota to enhance response to cancer immunotherapy.
[Cancer Cell] |
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| The Medicines and Healthcare products Regulatory Agency has approved the advanced melanoma medicine Opdualag (nivolumab-relatlimab) for patients from the age of twelve.
[Medicines and Healthcare Products Regulatory Agency] |
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| February 21 – 24, 2024
San Antonio, Texas, United States |
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| | Cedars-Sinai – Los Angeles, California, United States |
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| | Northwestern University – Chicago, Illinois, United States |
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| | Albert-Ludwigs-University Freiburg – Freiburg im Breisgau, Germany |
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| | Helmholtz Association of German Research Centres – Heidelberg, Germany |
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| | BC Cancer – Vancouver, British Columbia, Canada |
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Cancer Stem Cell News
Cell Therapy News
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Mammary Cell News
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