 | | Vol. 10.04 – 5 February, 2024 |
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| The long-lasting O2 supply and photosynthetic cyanobacteria-secreted extracellular vesicles could jointly promote angiogenesis and accelerate the wound healing process.
[Nature Communications] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
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| The progression of a BRAF-mutant mouse melanoma was suppressed in vivo upon YAP1 ablation in cancer-associated fibroblasts.
[Oncogene] |
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| By observing confluent Madin–Darby canine kidney (MDCK) epithelial cells expressing fluorescent biosensors, investigators demonstrated that calcium transients in a single cell caused Prostaglandin E2-mediated radial spread of PKA activation in neighboring cells.
[eLife] |
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| The hybrid hydrogel system accelerated the wound healing process in a full-thickness skin defect mice model, and the histological staining results demonstrated that it significantly promoted collagen deposition and vascularization.
[International Journal Of Biological Macromolecules] |
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| Researchers showed that Bmal1 had a context-dependent role in mouse melanoma tumor growth. Loss of Bmal1 in YUMM2.1 or B16-F10 melanoma cells eliminated clock function and diminished hypoxic gene expression and tumorigenesis, which could be rescued by ectopic expression of HIF1α in YUMM2.1 cells.
[Nature Communications] |
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| A tumor-metastasis-mimicked Transwell-integrated organoids-on-a-chip platform for precisely evaluating tumor metastatic potential was developed.
[Small] |
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| Using melanoma cell lines, investigators defined culture conditions for the reproducible three-dimensional growth of melanospheres to investigate putative cancer stem cell populations.
[British Journal Of Dermatology] |
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| Scientists found that the CoREST repressor complex was a critical mediator of the major distinct melanoma phenotypes and that corin treatment of melanoma cells led to phenotype reprogramming.
[JCI Insight] |
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| The authors spotlight the milestones and recent progress in the fabrication and utilization of vascularized skin models, as well as advances including the use of bioreactors, organ-on-a-chip devices, and organoid systems.
[Advanced Healthcare Materials] |
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| Almirall S.A. announced a strategic partnership with Microsoft to drive innovation and digital transformation, advance the research of medical solutions for dermatological diseases, and accelerate the digital transformation of the company.
[Almirall S.A.] |
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| March 21 – 23, 2024
Tokyo, Japan |
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| | Cancer Research UK Manchester Institute – Manchester, England, United Kingdom |
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| | University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | University Hospital of Muenster – Münster, Germany |
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| | Karolinska Institutet – Solna, Sweden |
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| | Northwestern University – Chicago, Illinois, United States |
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