 | | Vol. 10.05 – 12 February, 2024 |
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| The antioxidative active-shrinkage hydrogel relieved overactivated inflammation, prevented cellular apoptosis, and promoted fibroblast migration in vitro by reducing excessive reactive oxygen species.
[Advanced Materials] |
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| PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
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| Investigators performed longitudinal single-cell RNA-sequencing in individuals with psoriasis receiving IL-23 inhibitor therapy. They demonstrated that IL-23 blockade causes marked gene expression shifts, with fibroblast and myeloid populations displaying the most extensive changes at day 3.
[Nature Communications] |
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| The authors compared human tenocyte and dermal fibroblast behavior under standard and macromolecular crowding conditions to inform future studies in tendon engineering.
[Materials Today Bio] |
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| Researchers investigated the effects of green cocoon-derived sericin on human keratinocytes using lactate dehydrogenase activity to indicate damage reduction.
[Scientific Reports] |
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| Cells grown on plates coated by molecular collagen I, but not fibrillar collagen I, acquired certain resistance against UVB damages, as shown by increased survival and reduced apoptosis.
[Archives Of Biochemistry And Biophysics] |
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| Investigators identified ANKRD1 as a mesenchymal-specific transcriptional coregulator under direct androgen receptor negative control in human dermal fibroblasts and a key driver of cancer-associated fibroblasts conversion, independent of cellular senescence.
[Nature Communications] |
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| Researchers showed that the microphthalmia-associated transcription factor (MITF), a lineage addition oncogene that coordinates many aspects of melanocyte and melanoma biology, played a nontranscriptional role in shaping the DNA damage response.
[Genes & Development] |
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| In an imiquimod-induced psoriasis mouse model, saracatinib effectively blocked mixed lineage kinase domain-like protein (MLKL) phosphorylation and inflammatory responses in vivo.
[Cell Death & Disease] |
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| The authors identified ITGA3 gene as marked by a super-enhancer element in the Epgn3 invasive cells. Silencing of ITGA3 enhanced invasiveness in both in vitro and in vivo systems suggesting it as a negative regulator of invasion.
[JCI Insight] |
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| Scientists focus on the key cytoplasmic and nuclear mechanosensitive structures that are critical for the mammalian skin development and homeostatic maintenance.
[Current Opinion In Cell Biology] |
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| The authors highlight the current state of the art in nanozyme-engineered hydrogels for anti-inflammatory and skin regeneration applications.
[Nano Letters] |
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| Universities must declare all their retractions and launch investigations into misconduct cases; a Nature analysis reveals that since 2021 there have been more than 17,000 Chinese co-authored retractions.
[Nature News] |
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| April 4 – 5, 2024
Cincinnati, Ohio, United States |
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| | Universitätsklinikum Ulm – Ulm, Germany |
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| | Pfizer – Multiple Locations, United States |
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| | Cancer Research UK Manchester Institute – Manchester, England, United Kingdom |
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| | University Hospital of Muenster – Münster, Germany |
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| | University of Birmingham – Birmingham, England, United Kingdom |
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