 | | Vol. 6.25 – 13 July, 2020 |
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| Investigators revealed a function for the metastasis-associated phosphatase of regenerating liver 3 (PRL3) in melanocyte stem cell regeneration.
[Developmental Cell] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
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| Scientists showed that exit from the stem cell compartment in mammalian epidermis was characterized by pulsatile ERK MAPK activity.
[Proceedings of the National Academy of Sciences of the United States of America] |
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| The authors used biomaterial-based approaches and bioengineered techniques to develop a 3D skin model with layers of endothelial cell networks, dermal fibroblasts, and multilayered keratinocytes.
[Biofabrication] |
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| Investigators observed increased migration and reduced proliferation and differentiation when keratinocytes were co-cultured in media conditioned by human amniotic epithelial cell and human amniotic mesenchymal stem cells.
[Aging] |
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| Researchers showed for the first time that senescent cells were tumor promoters, not tumor initiators, and that they stimulated skin carcinogenesis by elevating p38 MAPK and MAPK/ERK signaling.
[Cancer Research] |
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| The authors have identified a unique dual role of BRD4 in melanoma cell migration/invasion, and in maintaining innate-immune checkpoint that might prevent macrophage mediated eradication of metastatic melanoma cells.
[Journal of investigative Dermatology] |
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| Scientists investigated the effect of BRN2 expression in melanoma cells with no or low constitutive expression using a doxycycline-inducible system.
[Oncogenesis] |
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| Investigators demonstrated that IL-22 might play an anti-apoptosis role on keratinocytes to balance cell proliferation and apoptosis in psoriatic epidermis.
[Apoptosis] |
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| Scientists uncovered a relationship between geometric features at perimeter regions of melanoma aggregates, and reprogramming to a stem cell-like state through histone marks H3K4Me2 and H3K9Ac.
[Communications Biology] |
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| This review describes the current understanding of the origin, different types, anatomical location, and genetics of adipose tissue as well as discussing the properties of adipose-derived stem cells and their promising applications for tissue engineering, scarring, and wound healing.
[Journal of Clinical Medicine] |
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| The authors look at spontaneously occurring animal ‘models’ of melanoma and discuss their relevance to the different types of melanoma found in humans.
[Journal of Pathology] |
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| Merakris Therapeutics, LLC. announced that the Centers for Medicare & Medicaid Services has assigned a Healthcare Common Procedure Coding System product code Q4248 for its topical skin graft substitute, Dermacyte Matrix.
[Merakris Therapeutics, LLC.] |
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| JS InnoPharm Ltd announced the enrollment of the first patient in a Phase I, open-label, monotherapy dose-escalation and expansion study of JSI-1187, the company’s lead investigational drug candidate targeting the enzymes ERK1 and ERK2.
[JS INNOPHARM LTD] |
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| International students completing their medical and doctoral degrees in the US are wrestling with frustration and uncertainty following the release of federal rules this week that could bar them from staying in the country.
[STAT] |
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| August 17 – August 19
Virtual |
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| | Ludwig Boltzmann Gesellschaft GmbH – Vienna, Austria |
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| | The Wistar Institute – Philadelphia, Pennsylvania, United States |
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| | King’s College London – London, United Kingdom |
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| | Bristol Myers Squibb РMontr̩al, Quebec, Canada |
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| | Brigham and Women’s Hospital – Boston, Massachusetts, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
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Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
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Neural Cell News
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