| Vol. 7.23 – 28 June, 2021 |
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| Real-time cell migration analysis, measuring wound closure rates over 24 hours, revealed that 18αGA essentially blocked wound closure whereas hexokinase and GSK-7975A showed relatively minimal effects. [Journal of Cellular Physiology] |
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PUBLICATIONSRanked by the impact factor of the journal |
| DERMAL STEM CELLS & TISSUE REGENERATION |
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| Scientists investigated the potential effects of Staphylococcus aureus on dermal fibroblasts as key cells for tissue repair. [FASEB Journal] |
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| Researchers presented for the first time, a novel approach to generate 3D multilayer tissue models in microfluidic platforms. [Scientific Reports] |
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| Scientists showed that patients with psoriasis had increased levels of matrix metalloproteinase13 protein in skin lesions and serum samples. [Scientific Reports] |
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| Researchers investigated the roles of individual cell types involved in burn wound healing following photobiomodulation treatments and noted discrete effects on epithelium, fibroblasts, and macrophage functions. [Scientific Reports] |
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| Scientists studied the effects of psoriatic dermal mesenchymal stem cells on the proliferation, differentiation, and migration of keratinocytes and the underlying mechanisms. [Dermatology] |
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| The migration ability and the changes of matrix metallopeptidase 9 (MMP-9) and MMP2 levels were determined using wound healing, transwell and Western blot assays. [Journal of Molecular Histology] |
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| Experimentally, researchers performed in vitro target validation, developed a new traceable spontaneously metastasising murine melanoma model for in vivo validation, and employed histology to confirm drug action in harvested tumour tissues. [British Journal of Cancer] |
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| Investigators demonstrated efficient T cell transduction with the melanoma-reactive TIL1383I TCR through culturing with interleukin 7 in the absence of CD3 activation. [Scientific Reports] |
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| Since the last decade induced pluripotent stem cells has been revolutionizing the field of wound healing and skin tissue engineering. Despite the current progress, safety and heterogeneity among iPSC lines are still major hurdles in addition to the lack of large animal studies. [Advances in Wound Care] |
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| BioNTech SE announced that the first patient has been treated in its BNT111 Phase II cancer vaccine trial. The study was evaluating the Company’s therapeutic cancer vaccine candidate BNT111 in combination with Libtayo® in patients with anti-PD1-refractory/relapsed unresectable Stage III or IV melanoma. [BioNTech] |
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| CUTISS AG, a Swiss clinical-stage life sciences company focused on skin regenerative medicine and tissue engineering, has unveiled the world’s first automated machine to produce customized skin tissue grafts for adults and children with severe skin injuries, such as deep burns. [Cutiss, AG.] |
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| October 27 – 29, 2021 Tokyo, Japan |
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| University of Erlangen-Nuremberg – Erlangen, Germany |
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| The University of British Columbia – Vancouver, British Columbia, Canada |
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| Brigham and Women’s Hospital – Boston, Massachusetts, United States |
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| University of Hawaii Cancer Center – Honolulu, Hawaii, United States |
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| Ulsan National Institute of Science and Technology – Ulsan, South Korea |
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