 | | Vol. 8.00 – 10 January, 2022 |
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| A proteome map of COVID-19 skin was established and the susceptibility of human-induced pluripotent stem cell-derived skin organoids with hair follicles and nervous system was investigated, to SARS-CoV-2 infection.
[Advanced Science] |
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| PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
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| PlncRNA-1 inhibited ZEB1 and activated MAPK1 signaling through upregulating EZH2, thereby enhancing the proliferation and differentiation of hair follicle stem cells and wound healing.
[Journal of Gene Medicine] |
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| | Investigators established a robust synthesis method for faceted nanoceria with primary particle diameters of 5–6 nm. The nanoceria were not cytotoxic to a human melanoma cell line at doses up to 400 μg/mL and were dose-dependently internalized by the cells.
[Journal of the American Chemical Society] |
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| Scientists confirmed that CXCL4 directly induced myofibroblast differentiation and collagen synthesis in different precursor cells, including endothelial cells, by stimulating endothelial-to-mesenchymal transition.
[Cell Reports] |
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| The authors investigated the efficacy of CD29- and CD44-targeted NIR-PIT (CD29-PIT and CD44-PIT, respectively) in the B16 melanoma model, which was highly pigmented.
[Oncoimmunology] |
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| Scientists examined the effect of selectively blocking the function of sCTLA-4 on in vitro immune responses from volunteer healthy or melanoma patient PBMC samples.
[Frontiers in Immunology] |
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| Caffeine has been studied as a potentiating agent in chemotherapy against some types of cancer, but there are few reports on its effects on melanoma. Researchers investigated caffeine’s ability to enhance the effects of dacarbazine in vitro.
[Bioorganic Chemistry] |
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| Investigators suggested that stiffer substrate enhanced melanoma development by upregulating SNF5 expression, and SNF5 was a key mediator of stiffer matrix-induced immune evasion of melanoma cancer cells.
[Translational Oncology] |
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| Vemurafenib-resistant A375.S2 cells were established, and the functional mechanism of the epidermal growth factor receptor (EGFR), serine–threonine kinase, and the extracellular signal-regulated kinase signaling induced by curcumin was investigated in A375.S2/VR cells in vitro.
[Environmental Toxicology] |
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| The authors demonstrated that the ablation of vitamin D receptors in keratinocytes greatly exacerbated dermal fibrosis in HOCl-induced scleroderma in mice.
[Biochemical and Biophysical Research Communications] |
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| Scientists summarize current understanding of the pathogenesis of psoriasis-related comorbidities and emerging discoveries of roles of cytokines targeted in psoriasis treatment, including tumor necrosis factor α and interleukins 12, 23, and 17.
[Inflammation Research] |
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| Investigators summarize the current cSCC literature with a focus on how differing clinical assessments within each of the five selected risk factors (perineural invasion, differentiation, depth of invasion, size, and location) can influence the evaluation of patient outcomes.
[Dermatology and Therapy] |
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| The authors review and study the market of the field of dermatology by reviewing various articles on tissue engineering. Tissue-engineered skin substitutes are future options for wound healing and tissue regeneration strategies.
[Tissue and Cell] |
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| AVITA Medical, Inc. announced that preclinical data successfully established proof of concept in two key areas of cell-based gene therapy – skin rejuvenation and epidermolysis bullosa.
[AVITA Medical, Inc.] |
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| February 10 – 12, 2022
Lorne, Victoria, Australia |
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| | Howard Hughes Medical Institute – Dallas, Texas, United States |
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| | Pfizer – Boulder, Colorado, United States |
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| | University Hospital of Lausanne – Lausanne, Vaud, Switzerland |
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| | Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
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| | Heidelberg University – Heidelberg, Germany |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
