 | | Vol. 8.03 – 31 January, 2022 |
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| ERBB3 binding protein 1 (Ebp1) expression was substantially higher in malignant melanoma (MM) than it was in normal skin, and Ebp1 was linked to the clinical stage and lymph node metastases of patients with MM.
[Cancer Cell International] |
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| PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
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| In controlled in vitro assays, it was found that Acanthus ebracteatus Vahl. extract and verbascoside at various concentrations induced dermal papilla cell proliferation which was indicated by an increase in the number of cells in the S and G2/M phases of the cell cycle.
[Scientific Reports] |
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| Researchers discovered that proper micro-injury effectively induced hair regeneration by activating the hair follicle stem cell proliferation and migration downwards to the hair matrix, finally shifting the hair follicle stage from telogen into anagen.
[Stem Cells and Development] |
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| By investigating the role of ARAF in NRAS-driven mouse melanoma through mass spectrometry experiments followed by a functional siRNA-based screen, scientists unexpectedly identified MITF as a direct ARAF partner.
[Communications Biology] |
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| Investigators showed that activation of apelin receptor (APLNR) upregulated IFN-γ signaling in melanoma cells through APLNR mediated β-arrestin 1 but not β-arrestin 2 recruitment.
[Biochemical Journal] |
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| SAMiRNA-AR68 could be efficiently delivered to human follicle dermal papilla cells and hair follicles, and this treatment decreased the androgen receptor mRNA and protein levels.
[Scientific Reports] |
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| Silencing of T cell immunoglobulin and mucin domain 3 (TIM-3) shuttled by MV3 cells-derived exosomes improved CD4+ T cell immune function and inhibited macrophage M2 polarization to attenuate the growth and metastasis of melanoma cells.
[Translational Oncology] |
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| To investigate the role of cell senescence in systemic sclerosis (SSc), the authors analyzed telomere shortening in SSc patients and the effect of targeting DNA damage in the bleomycin model of skin fibrosis.
[Immunity & Ageing] |
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| Scientists investigated the function of itraconazole-induced AMP-activated protein kinase alpha in melanoma progression through ERK signaling.
[Cell Biochemistry and Biophysics] |
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| The authors analyze and discuss the novel therapies for advanced basal cell carcinoma and squamous cell carcinoma to obtain a sharper perspective of the available treatment options.
[Advances in Therapy] |
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| Scientists focus on new immunotherapeutic approaches studied in advanced melanoma previously treated by anti-programmed cell death 1 (PD-1) receptor or anti-cytolytic T-lymphocyte-associated protein 4 (CTLA-4) antibodies.
[Current Opinion in Oncology] |
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| Evaxion Biotech A/S announced it received clearance from the Australia Therapeutic Goods Administration to initiate a Phase IIb trial of its patient specific cancer immunotherapy EVX-01 in combination with Merck & Co., Inc.’s anti-PD-1 therapy KEYTRUDA®.
[Evaxion Biotech A/S] |
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| April 6 – 9, 2022
Heidelberg, Germany |
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| | Albert Einstein College of Medicine – Bronx, New York, United States |
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| | Boston University Department of Dermatology – Boston, Massachusetts, United States |
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| | Weill Cornell Medical College – New York, New York, United States |
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| | University of California Los Angeles – Los Angeles, California, United States |
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| | Howard Hughes Medical Institute – Dallas, Texas, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
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Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
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Neural Cell News
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Pancreatic Cell News
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