 | | Vol. 8.29 – 26 September, 2022 |
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| By combining mouse genetics, single-cell and spatial transcriptomics, lineage tracing and quantitative modelling, researchers provided evidence of a hierarchical model of tumor growth that mirrored the cellular and molecular logic underlying the cell-fate specification and differentiation of the embryonic neural crest.
[Nature] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
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| Investigators described the development and characterisation of an irreversible lysyl oxidase inhibitor, PXS-6302.
[Nature Communications] |
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| Scientists found that the three-dimensional structure of the skin was completely regenerated in full-thickness skin incisions made before embryonic day 13.
[Scientific Reports] |
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| Antibiotic-anesthetic smart systems obtained by ionic complexation of polyelectrolytes with ciprofloxacin and lidocaine were obtained as films and hydrogels.
[Scientific Reports] |
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| Researchers showed that USP7 downregulation induced cellular senescence, arresting melanoma growth in vivo and proliferation in vitro in BRAF- and NRAS-mutant melanoma.
[Cell Reports] |
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| Scientists used two in vitro models, melanoma-conditioned media and indirect co-culture of keratinocytes with melanoma cells, to activate immortalized keratinocytes towards cancer-associated ones.
[Cell Communication and Signaling] |
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| The authors focus on the central role of the cell, extracellular matrix, and tissue mechanics in regulating tissue repair by controlling myofibroblast action, and also discuss how therapies based on mechanical intervention potentially ameliorate wound healing outcomes.
[Cold Spring Harbor Perspectives in Biology] |
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| Scientists present a narrative review on the roles of melanocytes in alopecia areata pathogenesis, aiming to provide a better understanding of this disease from the melanocyte’s perspective.
[Clinical Reviews in Allergy & Immunology] |
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| Demis Hassabis and John Jumper, both at DeepMind in London, were recognized for creating the tool that has predicted the 3D structures of almost every known protein on the planet.
[Nature News] |
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| November 6 – 8, 2022
Seville, Spain |
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| | Cedars-Sinai – Los Angeles, California, United States |
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| | Netherlands Cancer Institute (AVL) – Amsterdam, Netherlands |
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| | The National Psoriasis Foundation – Alexandria, Virginia, United States |
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| | National Research Council Canada – Toronto, Ontario, Canada |
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| | Lehigh University – Bethlehem, Pennsylvania, Untied States |
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