 | | | Vol. 8.32 – 24 October, 2022 |
|
|
|
| Researchers found that the RNA helicase DDX5 was downregulated in keratinocytes from the inflammatory skin lesions in patients with atopic dermatitis and psoriasis, and that mice with keratinocyte-specific deletion of Ddx5 were more susceptible to cutaneous inflammation.
[Nature Immunology] |
|
|
|
 |
| PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
|
|
|
| Scientists demonstrated that restriction of Gli2 expression, the major transcriptional activator of the sonic hedgehog signaling pathway, was a prerequisite for cochlear hair cell differentiation.
[Proceedings of the National Academy of Sciences of the United States of America] |
|
|
|
| Researchers evaluated the therapeutic potential of the secretome of human umbilical cord mesenchymal stem cells for dermatological diseases in adult human skin cells, ex vivo skin tissue, and a 3D skin model.
[Cell and Tissue Research] |
|
|
|
| Scientists determined the exact stage when nestin-expressing outer root sheath stem/precursor cells or their descendants appeared during hair follicle morphogenesis, and whether they were present in adult hair follicles.
[Scientific Reports] |
| |
|
|
| Investigators showed that wildtype RAC1 was a critical driver of growth and drug resistance, but only in a subset of melanomas with elevated markers of de-differentiation. Similarly, SRC inhibition also selectively sensitized de-differentiated melanomas to BRAF inhibition.
[npj Precision Oncology] |
|
|
|
| Researchers investigated the effects of metformin at epithelial-mesenchymal transition (EMT) in melanoma cell lines B16-F10 and A-375, in vitro, and the impact of EMT downregulation on melanoma progression in vivo.
[Scientific Reports] |
|  |
|
|
|
| The authors review how ILC2s integrate epithelial signals and neurogenic components to preserve the tissue microenvironment and modulate inflammation, highlighting recent findings suggesting neuro-epithelial-ILC2 crosstalk.
[Trends in Immunology] |
|
|
|
| Scientists describe the characteristics of wound healing, concentrating on the production and functions of extracellular vesicles (EVs) derived from specific skin cells, and provide new ideas for wound therapy using EVs.
[Burns & Trauma] |
|
|
|
|
| | Concerns about image integrity have so far led to 17 retractions, corrections or expressions of concern for papers co-authored by geneticist Gregg Semenza. [Nature News] |
|
|
|
|
| November 7 – 9, 2022
Singapore, Singapore |
|
|
|
|
|
| | The University of British Columbia – Vancouver, British Columbia, Canada |
|
|
|
| | Wellcome Genome Campus – Saffron Walden, United Kingdom |
|
|
|
| | IQVIA – Toronto, Ontario, Canada |
|
|
|
| | University College Dublin – Dublin, Ireland |
|
|
|
| | NCI – Bethesda, Maryland, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
