| Vol. 8.33 – 31 October, 2022 |
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| Investigators constructed a double-sided thermoresponsive mechanoactive hydrogel that combined good flexibility, self-healing, wet-tissue adhesion, and antibacterial functions. [ACS Nano] |
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PUBLICATIONSRanked by the impact factor of the journal |
| DERMAL STEM CELLS & TISSUE REGENERATION |
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| The authors revealed that microenvironmental reprogramming via control over reciprocal cellular interactions enabled hair follicle induction in vitro. A key approach was to modulate spatial distributions of epithelial and mesenchymal cells in their spontaneous organization. [Science Advances] |
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| Fibulin 7 interacted with structural extracellular matrix and matricellular proteins, and the overexpression of fibulin 7 in primary keratinocytes resulted in slower proliferation and suppressed differentiation. [EMBO Reports] |
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| Scientists used in vitro RNA-sequencing to show that the Hippo signaling pathway was involved in hair cell damage and self-repair processes. [NPJ Regenerative Medicine] |
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| Researchers demonstrated that epithelial cell–specific IκBζ-deficient (NfkbizΔK5) mice showed spontaneous skin inflammation with increased abundance of Staphylococcus aureus on the skin. [Science Immunology] |
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| Scientists found that melanoma cells harbored constitutively high CDK12 activity, and that its inhibition decreased the expression of long genes containing multiple exons, including many genes involved in DNA repair. [Nature Communications] |
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| The latest studies on the application of carbon nanomaterials including graphene oxide, reduced graphene oxide, carbon dots, carbon quantum dots, carbon nanotubes, carbon nanofibers, and nanodiamonds in wound dressing applications are evaluated. [Biomaterials Science] |
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| The authors summarize the current evidence linking nuclear factor (erythroid-derived 2)-like 2 (NRF2) to skin pathophysiology and discuss some recent modulators of NRF2 activity that have shown a therapeutic efficacy in skin protection against tumor initiation and common inflammatory skin conditions. [Biofactors] |
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| For the next 5 years, the National Science Foundation (NSF) will no longer require universities and other organizations to cover 30% of an award from its major research instrumentation program, which funds new equipment. [Science News] |
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| December 4 – 7, 2022 Banff, Alberta, Canada |
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| The University of Texas M. D. Anderson Cancer Center – Houston, Texas, United States |
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| Northwestern University – Chicago, Illinois, United States |
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| The University of British Columbia – Vancouver, British Columbia, Canada |
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| Wellcome Genome Campus – Saffron Walden, England, United Kingdom |
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| IQVIA – Toronto, Ontario, Canada |
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