 | | Vol. 9.03 – 30 January, 2023 |
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| In human melanoma cell lines and patient-derived xenografts, non-homologous end-joining-targeting by a DNA-PKCS inhibitor prevented/delayed acquired MAPKi resistance by reducing the size of ecDNAs and complex genomic rearrangements early on combination treatment.
[Cancer Discovery] |
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| PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
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| L-17A, a cytokine important for the development of psoriatic lesions, contributed to FXYD3 expression in human primary keratinocytes.
[Cellular & Molecular Immunology] |
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| The authors’ wearable edgeless skin constructs showed enhanced dermal extracellular matrix deposition and mechanical properties compared to conventional constructs.
[Science Advances] |
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| Researchers demonstrated a critical role for galectin-7, a β-galactoside-binding protein preferentially expressed in skin tissue, during non-melanoma skin cancerdevelopment.
[Cell Death & Differentiation] |
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| To elucidate the effects of the cellular and physical microenvironment on tongue squamous cell carcinoma, investigators developed a collagen cell disc, with double dish under a rotational culture method to generate cancer–stroma interactions and to create fluid flow stimulation.
[Human Cell] |
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| The authors investigated the influence of different succinic acid concentrations on the process of cellular senescence under normal and hypoxic conditions.
[Biochemistry and Biophysics Reports] |
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| Pharmacological blocking or genetic ablation of both endothelin receptors, ETA and ETB, impeded dermal sheath contraction and halted follicle regression.
[Nature Cell Biology] |
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| Scientists developed a natural biological adhesive from snail mucus gel, which consisted a network of positively charged protein and polyanionic glycosaminoglycan.
[Nature Communications] |
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| MALAT1 was decreased in diabetic mouse wound tissue and could promote keratinocyte biological functions. MALAT1 could bind to miR-106a-5p to modulate the expression of ZNF148, a target gene of miR-106a-5p.
[Regenerative Medicine] |
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| Investigators evaluate the increasing body of literature that argues the “double-edged” consequences of autophagy manipulation in cancer therapy, with a particular focus on highly plastic and mutagenic melanoma.
[Current Treatment Options in Oncology] |
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| The Prevent Cancer Foundation® announced funding for eight scientists who were researching cancer prevention and early detection. Each scientist had been awarded $100,000 for two years. Areas of focus included the blood, breast, colon, lung and skin
[The Prevent Cancer Foundation] |
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| April 17 – 19, 2023
Freiburg im Breisgau, Germany |
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| | AstraZeneca – Cambridge, England, United Kingdom |
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| | Dresden University of Technology – Dresden, Germany |
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| | Imperial College London – London, England, United Kingdom |
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| | The University of Cambridge – Cambridge, England, United Kingdom |
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| | BioMed X Institute – New Haven, Connecticut, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
