| Vol. 9.05 – 13 February, 2023 |
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| Researchers showed that fingerprint ridges were epithelial structures that underwent a truncated hair follicle developmental program and failed to recruit a mesenchymal condensate. [Cell] |
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PUBLICATIONSRanked by the impact factor of the journal |
| DERMAL STEM CELLS & TISSUE REGENERATION |
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| Different gelatin methacrylate/nano-cellulose bioink formulations were used to develop heterogeneous tissue-engineered skin containing layers of fibroblast networks with larger pores, basal layers with smaller pores, and multilayered keratinocytes. [Biomaterials Science] |
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| Investigators assessed the suitability of the skin parallel artificial membrane permeability assay model for prediction of skin permeation of 2-phenoxyethanol. [International Journal Of Pharmaceutics] |
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| Application of exogenous human beta-defensin 2 provided protection against V8, irrespective of timeline of application or native peptide folding, raising the prospect of simple peptide analogues as therapeutics. [Scientific Reports] |
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| To study the acceleration of the wound healing process, researchers bound epidermal growth factor and fibroblast growth factor 1 to heparinized human acellular amniotic membrane. [Journal Of Biomedical Materials Research Part A] |
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| The authors investigated the effect of LL-37 on CXCL10 induced by damage-associated molecular patterns and pathogen-associated molecular patterns in immortalized oral keratinocytes, RT7. [Inflammation] |
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| Transcriptome analysis of rat skin tissues suggested that viaminate had significant regulatory effects on fatty acid metabolism and cellular keratinization pathways. [Naunyn-Schmiedebergs Archives Of Pharmacology] |
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| Hair follicle stem cells (HFSCs) were isolated using the technique of immunohistochemistry from the cervical spinal skin tissue samples from the fetal sheep, and the miR-133a-3p expression was confirmed using quantitative reverse-transcription PCR and western blotting experiments from the isolated HFSCs. [Animal Biotechnology] |
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| Scientists described a fluorescence-activated cell sorting-based whole genome-wide CRISPR-Cas9 screen to uncover regulators of AXL expression. [Molecular Cancer Research] |
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| A high-throughput strategy combined with MALDI TOF/TOF-MS and molecular docking was developed to screen peptides with antitumor functions from oyster hydrolysate. Three dominant peptides were predicted to have similar functions to IL-2 via molecular docking. [Food & Function] |
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| The authors provide an overview of the biological role of galectins in repair and regeneration, focusing on four main phases of skin repair using basic wound models. [Expert Opinion On Therapeutic Targets] |
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| To systematically elucidate how ΔNp63α affected keratinocyte senescence via epigenetic regulation, scientists comprehensively compiled the literature on the roles of ΔNp63α in keratinocyte senescence and epigenetics in cellular senescence. [Epigenetics] |
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| Onconova Therapeutics, Inc. announced that the 2nd of two evaluable participants in a Phase II program evaluating rigosertib monotherapy in advanced squamous cell carcinoma complicating recessive dystrophic epidermolysis bullosa achieved a complete response of all cancerous skin lesions following 4 treatment cycles and remains on oral rigosertib. [Onconova Therapeutics, Inc.] |
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| March 31, 2023 Amsterdam, The Netherlands |
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| Khalifa University – Abu Dhabi, United Arab Emirates |
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| University of Mississippi Medical Center – Jackson, Mississippi, United States |
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| Imperial College London – London, England, United Kingdom |
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| Dresden University of Technology – Dresden, Germany |
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| Imperial College London – London, England, United Kingdom |
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