| Vol. 9.14 – 24 April, 2023 |
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| In in vitro studies, cells could be attached, alive, and migrate through the prepared hydrogel scaffold. The therapeutic effect of the cell-seeded hydrogels was tested in the full-thickness animal wound model. [International Journal of Biological Macromolecules] |
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| PUBLICATIONSRanked by the impact factor of the journal |
| DERMAL STEM CELLS & TISSUE REGENERATION |
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| Cell studies showed biocompatibility and non-toxicity of the hydrogel along with the promotion of cell migration, and the in vivo data revealed enhanced tissue regeneration and recovery within 17 days in the studied animals. [International Journal of Biological Macromolecules] |
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| The authors described a chronic wound murine model and its cellular senescence profile, including the senescence-associated secretory phenotype. [Aging-Us] |
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| Scientists investigated the effects of neuropeptide Y (NPY) on adipose-derived stem cells (ASCs) proliferation and growth factors expression and secretion, the effects of NPY on skin fibroblasts, and the effects of NPY combined with ASCs on Type 2 diabetes wound healing. [Tissue Engineering And Regenerative Medicine] |
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| Researchers used human dermal papilla cells isolated from androgenic alopecia (AGA) patients’ hair that expressed 5α-R type-1 as well as the androgenic receptor at high levels to explore the potential use of the Avicennia marinaextract and of avicequinone C as anti-AGA agents. [PLOS One] |
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| To evaluate the 2D coculture model consisting of keratinocytes and dendritic cells, different weak to moderate sensitizing fragrance chemicals were tested in the coculture activation test, consisting of HaCaT keratinocytes and THP-1 cells. [Contact Dermatitis] |
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| ATAC-seq was used to study brother of regulator of imprinted sites (BORIS)-mediated chromatin accessibility alterations in melanoma cells harboring an intermediate melanocytic state. [Pigment Cell & Melanoma Research] |
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| The impact of miR-199a-5p produced by adipose-derived stem cells on malignant melanoma skin cancer was investigated in 30 pair tumor tissues and adjacent tissues obtained from skin cancer patients. [Biotechnology and Genetic Engineering Reviews] |
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| Overexpression of miRNA-708 successfully reduced NRAS protein levels in melanoma, leukemia, and lung cancer cell lines with NRAS mutations, resulting in suppressed cell proliferation, anchorage-independent growth, and promotion of reactive oxygen species-induced apoptosis. [PLOS One] |
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| Scientists discuss the current immunotherapeutic regimens used to treat malignant melanoma, the molecular and cellular mechanisms involved, and current clinical studies that have investigated the use, efficacy, and adverse events of immunotherapy in melanoma. [Critical Reviews In Oncology/Hematology] |
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| The authors highlight recent studies that investigated therapeutic potential of various mesenchymal stem/stromal cells (MESCs) and MSC-extracellular vesicles in skin damages and wounds. [Human Cell] |
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| Incyte announced that the European Commission has granted a marketing authorization for Opzelura® (ruxolitinib) cream 15mg/g for the treatment of non-segmental vitiligo with facial involvement in adults and adolescents from 12 years of age. [Incyte] |
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| May 9 – 11, 2023 Scottsdale, Arizona, United States |
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| University of Gothenburg – Gothenburg, Sweden |
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| Case Western Reserve University – Cleveland, Ohio, United States |
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| STEMCELL Technologies, Inc. – Vancouver, British Columbia, Canada |
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| Harvard Medical School – Boston, Massachusetts, United States |
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| Oslo University Hospital – Oslo, Norway |
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