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| Scientists demonstrated that a specific stem cell population, distant from the original injury, originated long-lasting wound memory progenitors residing in their own niche.
[Nature Cell Biology] |
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| PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
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| Researchers showed that genetic deletion of the mouse homolog ZFP750 resulted in loss of epidermal barrier function, which was associated with a substantial reduction of ceramides, nonpolar lipids.
[Science Advances] |
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| Scientists found that tumor cells may achieve a “tumor microenvironment remodeling pattern” through an “immune pressure-sensing model”, in which they could choose to reshape the TME into a barrier environment or a cold environment according to the immune pressure.
[Cell Reports] |
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| Investigators demonstrated that cultured human epidermal stem cells responded to a small drop in temperature through thermoTRP channels via mTOR signaling.
[EMBO Reports] |
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| Researchers found that the activity of Nucleotide Excision Repair (NER) determined heterogeneity of the mutation rates across skin cancer genomes and that transcription-coupled NER extended beyond the gene boundaries reducing the intergenic mutation rate.
[Nature Communications] |
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| Transgelin (TAGLN) knockdown could release USP1 retention and helped human skin fibroblasts resist UVA-induced damage.
[Cell & Bioscience] |
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| A zinc-based nanoscale metal−organic framework functioned as a carrier to deliver natural product berberine (BR) to form BR@Zn-BTB nanoparticles, which was further encapsulated by hydrogel with reactive oxygen species (ROS) scavenging ability to yield a composite system of BR@Zn-BTB/Gel (BZ-Gel).
[iScience] |
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| To evaluate the hazardous potential of BgP on human skin under UVA exposure, different experimental tools i.e., in chemico, in silico and in vitro were utilized.
[Chemico-Biological Interactions] |
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| Focusing on fibroblasts as main actors of keloid formation, scientists evaluated intra- and inter-keloid fibroblast heterogeneity by analysing their gene expression and functional capacities in order to improve the understanding of keloid pathogenesis.
[Experimental Dermatology] |
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| The authors focus on the specific roles and mechanisms of different mesenchymal stem cells-exosomes in wound healing, as well as the current limitations and various perspectives.
[Stem Cell Research & Therapy] |
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| Scientists discuss the relevance of receptor tyrosine kinases (RTK) signaling in the progression of cutaneous squamous cell carcinoma, and observations from clinical trials that used RTK inhibitors against cutaneous squamous cell carcinoma
[iScience] |
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| The Melanoma Research Alliance announced its new $6.3 million commitment to fund melanoma research, supporting 24 scientists at leading academic and medical institutions across the US and Europe, spanning the entire spectrum of the disease including prevention, diagnosis, treatment, and metastatic disease.
[Melanoma Research Alliance] |
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| More than 40 leading scientists have resigned en masse from the editorial board of a top science journal in protest at what they describe as the “greed” of publishing giant Elsevier.
[The Guardian] |
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| June 2 – 6, 2023
Chicago, Illinois, United States |
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| | University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | Institut Pasteur – Paris, France |
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| | Harvard T.H. Chan School of Public Health – Boston, Massachusetts, United States |
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| | University of Gothenburg – Gothenburg, Sweden |
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| | Case Western Reserve University – Cleveland, Ohio, United States |
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