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| Researchers used a new method known as cyclobutane pyrimidine dimer-capture-seq to map UV-induced cyclobutane pyrimidine dimers with high sequencing depth and single nucleotide resolution at sites of recurrent mutations in melanoma.
[Nature Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
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| In order to explore an effective treatment that could achieve multi-dimensional repair of the injured cornea, the authors combined modified mRNA technologies with adipose derived mesenchymal stem cells therapy.
[Molecular Therapy] |
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| Primary and immortalized adult dermal fibroblasts were expanded for two-three passages upon receiving. The cells were harvested, resuspended in PBS, and bioprinted into a 96-well plate with pluriSTEM media.
[Biofabrication] |
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| Scientists showed that in stratifying epithelia the polarity protein aPKCλ controls the reorganization from stress fibers to cortical actomyosin during differentiation and upward movement of cells.
[Scientific Reports] |
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| The authors demonstrated that murine melanocyte-specific Bmi1 deletion caused premature hair greying and gradual loss of melanocyte lineage cells.
[Pigment Cell & Melanoma Research] |
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| Investigators used single-cell and imaging-based spatial analysis to elucidate three microenvironmental neighborhoods surrounding the heterogeneous basal cell carcinoma tumor epithelia.
[Nature Communications] |
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| Biocompatibility and hemocompatibility were validated in vitro using human dermal fibroblasts and sheep blood, respectively.
[International Journal Of Biological Macromolecules] |
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| The authors hypothesized that positronium imaging would be sensitive to the in vitro discrimination of tumor-like three-dimensional structures built of melanoma cell lines with different cancer activities and biological properties.
[Scientific Reports] |
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| The data from TCGA corresponding to transcriptomic expression patterns for patients with skin cutaneous melanoma were downloaded and utilized to screen distinct molecular subtypes by a non-negative matrix factorization algorithm.
[Heliyon] |
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| The authors focused on highlighting changes that occur during psoriasis development at the level of lipid peroxidation products, including 4-hydroxynonenal, 4-oxononenal, malondialdehyde, and acrolein, and their influence on protein structures.
[Redox Biology] |
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| Scientists explore the core biology of extracellular vesicles, associated pharmacology, comprehension of immunogenic outcomes, and potential for long-term wound treatment with improved effectiveness and their nonacceptable side effects.
[Molecular Therapy – Nucleic Acids] |
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| Melanoma skin cancer is on the rise and 4,000 cases annually are linked to poverty, according to the Melanoma Focus charity, which argues that a VAT cut would reduce the number of deaths.
[The Guardian] |
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| June 4 – 7, 2023
Heidelberg, Germany |
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| | DFG Research Training Group – Berlin, Germany |
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| | University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | Institut Pasteur – Paris, France |
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| | Case Western Reserve University – Cleveland, Ohio, United States |
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| | STEMCELL Technologies, Inc. – Vancouver, British Columbia, Canada |
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