 | | Vol. 4.30 – 10 July, 2023 |
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| A 3D multicellular micropattern was successfully fabricated by arranging the hair follicle-related cells orderly distributed in the interval of vascular-cell networks via bioprinting technology.
[Materials Horizons] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
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| The released peptide-based TGFβ receptor II inhibitor inhibited the TGFβ1/p38 pathway, leading to improved cell migration and angiogenesis, and decreased inflammation.
[NPJ Regenerative Medicine] |
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| Scientists described an autologous skin model containing a functional resident skin immune system and a capillary network, providing a relevant tool to study the contribution of the immune system to skin diseases and inflammatory responses and to investigate resident skin cell interactions and drug development.
[Acta Biomaterialia] |
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| The molecular changes induced by Wnt4 were analyzed by RNA sequencing, immunofluorescence, Western blotting and qPCR in HaCaT cells and burn wound healing tissues.
[Burns & Trauma] |
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| The authors identified a tumor-intrinsic function of the orphan nuclear receptor NR2F6, regulating antitumor immunity, and found that genetic ablation of NR2F6 in a mouse melanoma model conferred a more effective response to PD-1 therapy.
[Science Advances] |
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| Researchers identified effective combinations of experimental small molecules with cold gas plasma for therapy in dermato-oncology. Combination effects of selected drugs and cold gas plasma were investigated with respect to oxidative stress, invasion, and viability.
[Journal of Advanced Research] |
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| Cancer-associated fibroblasts (CAFs) are critical for glutamine deprivation survival in melanoma. The authors assembled a CAFs-targeted, controlled-release nanodroplets for the combined delivery of the amino acid transporter ASCT2 inhibitor V9302 and GLULsiRNA.
[Journal Of Nanobiotechnology] |
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| Scientists investigated the impact of silica coated gold nanoparticle (Au@SiO2 NPs) on high glucose-induced keratinocyte complications.
[Life Sciences] |
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| Using a Niemann-Pick type C1 protein (NPC1) knock-out melanoma cell model, researchers found that the cellular phenotype of NPC was associated with a decreased pigmentation accompanied by low expression of the melanogenic enzyme tyrosinase.
[Journal Of Biological Chemistry] |
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| The authors review current advances in skin-on-chip models and their potential to elucidate biological mechanisms, and discuss strategies to recapitulate skin physiology on-chip, improving control over nanomaterials exposure and transport across cells.
[Trends In Biotechnology] |
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| Scientists discuss the role of dermal fibroblasts in the war against pathogens, as they have important immune functions in anti-infection immunity which should not be overlooked.
[Experimental Dermatology] |
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| Trial results for JNJ-2113 demonstrated a profile that supports its advancement into Phase III clinical development for moderate-to-severe plaque psoriasis in adult patients.
[Janssen Pharmaceutical Companies of Johnson & Johnson] |
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| August 3, 2023
New York, New York, United States |
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| | Karolinska Institutet – Solna, Sweden |
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| | BC Cancer Center – Vancouver, British Columbia, Canada |
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| | Brigham and Women’s Hospital – Boston, Massachusetts, United States |
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| | Sorbonne-Universite – Paris, France |
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| | Institut Pasteur – Paris, France |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
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Hepatic Cell News
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Intestinal Cell News
Mammary Cell News
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