| Vol. 9.27 – 14 August, 2023 |
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| Using a combination of zebrafish transgenesis coupled with human tissues, scientists demonstrated that GABAergic signaling between keratinocytes and melanocytes promoted melanoma initiation by BRAFV600E. [Cancer Discovery] |
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| PUBLICATIONSRanked by the impact factor of the journal |
| DERMAL STEM CELLS & TISSUE REGENERATION |
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| Researchers used the hair follicle to show that during growth, the mesenchymal niche of the hair follicle, the dermal papilla (DP), was maintained quiescent by the activity of Hdac1 and Hdac2 in the DP that suppressed the expression of cell-cycle genes. [Nature Communications] |
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| Investigators established a human tissue model of Darier disease to elucidate its pathogenesis and identify potential therapies. [JCI Insight] |
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| Scientists found that miR-186-5p regulated macrophage migration and proliferation to delay wound healing through the TGFβR2/Smad2/p38 molecular axes. [Environmental Toxicology] |
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| Investigators assessed the protective effect of sesamin on ultraviolet A (UVA)-irradiated keratinocytes and determined its potential antiphotoaging effect. [Journal Of Cosmetic Dermatology] |
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| Researchers investigated the effect of noncytotoxic concentrations of tranexamic acid on interleukin-17-induced human keratinocyte cells to determine the status of proliferative psoriatic keratinocytes. [Biomedicine & Pharmacotherapy] |
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| The authors investigated the potential regulatory mechanism of Spi-1 proto-oncogene (SPI1) in melanoma. The mRNA and protein levels were measured via qRT–PCR and Western blotting. [Journal of Cellular and Molecular Medicine] |
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| Researchers investigated α-Mangostin effect on melanoma growth, migration, and invasion and its possible molecular mechanism. [International Journal of Medical Sciences] |
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| Scientists investigated whether epigenetic drugs can improve the chemoresistance induced under hypoxia in cancer cells. [Biochemical and Biophysical Research Communications] |
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| The authors discuss tumor secretory factors involved in subverting tumor immunity and remodeling lymph nodes and highlight emerging therapeutic strategies. [Trends In Immunology] |
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| Early-career researchers who work in labs operated by the US National Institutes of Health (NIH) have hit a roadblock on their way to unionizing. [Science Insider] |
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| Sanofi will be the inaugural partner for the Scleroderma Research Foundation’s new clinical trial initiative to advance treatments for the rare autoimmune disorder of the skin and organs. [Fierce Biotech] |
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| September 20 – 23, 2023 Milan, Italy |
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| Creative Biolabs – New York, New York, United States |
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| Institut Pasteur – Paris, France |
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| Center for Excellence in Molecular Cell Science – Shanghai, China |
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| Beckman Laser Institute – Irvine, California, United States |
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| Duke University – Durham, North Carolina, United States |
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