 | | Vol. 9.29 – 28 August, 2023 |
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| Scientists used multimodal single-cell approaches, epigenetic assays, and allografting techniques to define a dermal fibroblast progenitor state and the mechanism that governed its differentiation potential.
[EMBO Journal] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
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| The authors visualized the spatio-temporal dynamics of Mg2+ in keratinocytes in response to H2O2, a type of reactive oxygen species, and found that it increased cytosolic Mg2+ levels.
[Communications Biology] |
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| Investigators identified Rab38 as a novel physiologic regulator of leucine-rich repeat kinase 2 (LRRK2) in melanocytes.
[Journal of Biological Chemistry] |
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| To investigate the potential mechanism, senescence-accelerated mouse prone 6 (SAMP6) was intragastrically administered with Bazi Bushen for nine weeks to induce skin homeostasis.
[Journal Of Cellular And Molecular Medicine] |
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| Researchers applied theoretical considerations to experiments both in vitro and in vivo to study the spread of interferon-γ in melanomas.
[Proceedings Of The National Academy Of Sciences Of The United States Of America] |
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| Scientists provided a novel mechanism connecting oncogenic signaling and the tumorigenic properties by a transforming growth factor-β1-stimulated clone 22 (TSC-22) family protein, THG-1.
[Cancer Science] |
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| Investigators designed a nanoparticulate system capable of sufficiently accumulating in the tumor and spleen to mediate local and systemic immune responses, respectively.
[Drug Delivery and Translational Research] |
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| Researchers investigated the effect of L-type amino acid transporter 1 (LAT1) inhibition on cancer metastasis using B16-F10 melanoma mouse models.
[Scientific Reports] |
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| Scientists found that interleukin-23 was highly expressed in the epidermis of psoriasis lesions and positively correlated with histological neutrophil infiltration and clinical psoriasis area and severity index scores.
[Clinical And Experimental Pharmacology And Physiology] |
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| The authors explore the molecular biology of α-MSH with particular emphasis into its tumor-related properties whilst elaborating the experimental evidence on the interplay between α-MSH/melanocortin 1 receptor axis, melanoma, and antitumor strategies.
[Journal of Translational Medicine] |
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| The US government has extended for six months a key symbolic agreement to cooperate with China in science and technology.
[Nature] |
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| October 4 – 6, 2023
Paris, France |
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| | Cedars-Sinai – Los Angeles, California, United States |
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| | University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | Creative Biolabs – New York, New York, United States |
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| | Helmholtz Association of German Research Centres – Heidelberg, Germany |
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| | Institut Pasteur – Paris, France |
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