 | | Vol. 9.30 – 11 September, 2023 |
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| The authors used sorbitol-treated human fibroblasts in 3D culture to study the consequences of hyperosmotic stress in the skin.
[Science Advances] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
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| Researchers successfully differentiated and established a pure culture of melanocytes. The melanocytes maintained their growth rate for a long time, approximately 200 days, and were functional.
[Stem Cell Research & Therapy] |
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| Investigators reported that the human papillomavirus type 8 (HPV8) E6 protein could subvert Hippo signaling by activating Transcriptional Enhanced Associate Domain transcriptional programs that inhibited the expression of keratinocyte differentiation markers.
[mBio] |
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| To evaluate scalp bacteria’s effect on human keratinocyte cellular activity, including that of the hair follicular keratinocytes, the expression of several longevity genes was examined using HaCaT cells.
[Bioscience, Biotechnology, and Biochemistry] |
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| Investigators tested whether the MISTRG6 strain of humanized mice could be transplanted with healthy or scleroderma human skin grafts. They found that healthy and scleroderma skin grafts retained skin and bone marrow–derived immune cells.
[Proceedings Of The National Academy Of Sciences Of The United States Of America] |
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| The authors found that N-terminal gasdermin D was aberrantly expressed in epidermis of skin lesion in psoriasis patients and imiquimod-induced psoriasis-like dermatitis mice.
[Cell Death & Disease] |
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| Researchers showed that the expression of the growth regulation by estrogen in breast cancer 1 (GREB1) splicing variant, isoform 4, was mediated by microphthalmia-associated transcription factor (MITF) in melanoma cells.
[Oncogene] |
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| Scientists investigated anti-atopic and anti-inflammatory activities of Sanguisorba hakusanensis ethanol extract both in vivo using NC/Nga mice and in vitro using human HaCaT keratinocytes.
[Scientific Reports] |
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| Researchers investigated the effects of exogenous kynurenine compounds on melanoma cells in vitro. They found that the various exogenous kynurenine compounds each displayed different levels of cytotoxicity, which were cell-line specific.
[Cell Biochemistry And Function] |
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| The authors provide a historical overview of the steps undertaken to obtain information on the lipid composition and organization in the stratum corneum of healthy skin and inflammatory skin disease.
[Progress in Lipid Research] |
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| The UK government announced that it will rejoin the European Union’s €95 billion research funding program known as Horizon Europe.
[ScienceInsider] |
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| October 1 – 4, 2023
Toronto, Ontario, Canada |
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| | Nottingham Trent University – Nottingham, England, United Kingdom |
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| | Cedars-Sinai – Los Angeles, California, United States |
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| | Creative Biolabs – New York, New York, United States |
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| | Center for Excellence in Molecular Cell Science – Shanghai, China |
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| | Institut Pasteur – Paris, France |
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