 | | Vol. 9.39 – 4 December, 2023 |
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| The authors used three human induced pluripotent stem cells lines to generate complex skin organoids with stratified skin layers and pigmented hair follicles, with different efficacies.
[Small] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
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| The study delineated the cellular attributes of microthermal zones, underscoring a temporally limited, subclinical inflammatory milieu concomitant with rapid re-epithelialization within 24 hours.
[Journal Of Investigative Dermatology] |
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| Investigators achieved highly efficient COL7A1 editing in primary recessive dystrophic epidermolysis bullosa keratinocytes and fibroblasts from two patients homozygous for the c.6508C>T mutation.
[Journal Of Investigative Dermatology] |
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| Human adipose tissue-derived exosomes incubation increased keratinocytes and fibroblast proliferation, migration, and extracellular matrix accumulation.
[Journal Of Physiology And Biochemistry] |
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| Researchers validated different engineered immortalized cell lines created from primary human keratinocytes as model systems to study epidermal function.
[Experimental Dermatology] |
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| The authors investigated hidradenitis suppurativa epithelial cells and demonstrated that hidradenitis suppurativa basal progenitors modulated their lineage restriction and gave rise to pathogenic keratinocyte clones, resulting in epidermal hyperproliferation and dysregulated inflammation.
[Proceedings Of The National Academy Of Sciences Of The United States Of America] |
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| Scientists investigated the role of Mahogunin Ring Finger 1 (MGRN1) on human melanoma cell morphology, adhesion, and expression of genes/proteins involved in an EMT-like transition.
[Cancer Letters] |
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| Treatment with recombinant DKK1 resulted in a decrease of cell growth in outer root sheath cells, whereas the use of a DKK1 neutralising antibody promoted hair growth.
[Cell Proliferation] |
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| Scientists compared the impact of an active form of vitamin D3 on mitochondrial morphology and bioenergetics in human squamous cell carcinoma and immortalized HaCaT keratinocytes.
[Free Radical Biology And Medicine] |
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| The authors summarize the role of dermal fibroblasts in cutaneous aging and inflammation, and discuss the underlying mechanisms by which dermal fibroblasts influence cutaneous aging and inflammation.
[Aging Cell] |
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| The whole genomes of 500,000 people in the UK Biobank will help researchers to probe our genetic code for links to disease.
[Nature News] |
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| January 22 – 25, 2024
Santa Fe, New Mexico, United States |
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| | Albert Einstein College of Medicine – Bronx, New York, United States |
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| | Helmholtz Association of German Research Centres – Heidelberg, Germany |
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| | BC Cancer – Vancouver, British Columbia, Canada |
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| | University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | Babraham Institute – Cambridge, England, United Kingdom |
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