 | | Vol. 6.27 – 9 August, 2021 |
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| Immunocytochemistry, angiogenesis assay, and western blot analysis of human dermal lymphatic endothelial cells were conducted to assess the involvement of substance P/neurokinin-1 receptor system in lymphangiogenesis.
[Ocular Surface] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| A codelivery strategy that combined the cascaded enzymes lactate oxidase/catalase and vascular endothelial growth factor siRNA to suppress tumor proliferation and angiogenesis synergistically was proposed.
[Advanced Healthcare Materials] |
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| Researchers discovered a novel role of Slit2-Robo signaling in glomerular vascularization. Slit2 is a secreted polypeptide that bound to transmembrane Robo receptors and regulated axon guidance as well as ureteric bud branching and angiogenesis.
[Journal of the American Society of Nephrology] |
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| The authors evaluated the efficacy of cryopreserved human embryonic stem cell-derived corneal endothelial cells to form a functional monolayer of corneal endothelium in rabbits and monkeys.
[Stem Cell Reports] |
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| Scientists revealed that MK2206 suppressed migration, proliferation, and inflammation in vascular smooth muscle cells. Moreover, MK2206 inhibited proliferation and inflammation of endothelial cells.
[Acta Pharmacologica Sinica] |
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| Nitric oxide (NO) fluorescent detection signal detected NO production in primary endothelial cells cultures incubated with anthocyanins or E2 in the absence and presence of estrogen receptor alpha or G protein‐coupled estrogen receptor selective antagonists.
[Journal of the American Heart Association] |
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| Concentrations of plasma vascular endothelial growth factor and circulating endothelial progenitor cells in control mice formed a circadian rhythm, which was diminished in the jet‐lag model.
[Journal of the American Heart Association] |
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| SARS-CoV-2 could extend beyond the trophoblast into the villous stroma, involving Hofbauer cells and capillary endothelial cells, in a small number of infected placentas.
[Archives of Pathology & Laboratory Medicine] |
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| Human umbilical vascular endothelial cells were cultured with or without COL-4A1 and TNF-α. Cell Counting Kit-8, wound-healing, Transwell and tube formation assays were used to evaluate cell proliferation, migration and angiopoiesis.
[Scientific Reports] |
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| Researchers hypothesized that gastrin might protect against heart injury after myocardial infarction by promoting angiogenesis. Downregulation of HIF-1α expression by siRNA reduced the proliferation, migration and tube formation of human umbilical vein endothelial cells.
[Scientific Reports] |
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| Investigators analyzed the role/number of endothelial progenitor cells, renal function, and pathological alterations in rats with chronic renal failure, and compared the results before and after supplementation with calcitriol in vivo.
[Journal of Steroid Biochemistry and Molecular Biology] |
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| The authors discuss aspects of physiological and molecular function centering around phospholipase C γ1 (PLCγ1) in the context of endothelial cells and provide a perspective for future investigation.
[Science Signaling] |
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| Scientists summarize the current understanding of exosome biogenesis and uptake, and discuss atherogenic and atheroprotective functions of exosomes secreted from these cell types.
[AAPS Journal] |
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| Investigators summarize the current knowledge of how different crosstalk between liver sinusoidal endothelial cells and other liver cells, including hepatocytes, hepatic stellate cells, macrophages, immune cells in liver and extra cellular matrix contribute to the physiological function and the progression from liver fibrosis to cirrhosis, or even to hepatocellular carcinoma.
[Digestive and Liver Disease] |
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| Relief Therapeutics, AG. reported that, via its newly acquired subsidiary, AdVita Lifescience GmbH, the Company has been granted Orphan Drug Designation by the US FDA for RLF-100, an inhaled formulation in development for the treatment of sarcoidosis.
[Relief Therapeutics, AG.] |
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| September 26 – October 1, 2021
Orlando, Florida, United States |
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| | The Scripps Research Institute – La Jolla, California, United States |
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| University Hospital of Cologne – Cologne, Germany |
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| | Medical College of Wisconsin – Milwaukee, Wisconsin, United States |
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| Baylor College of Medicine – Houston, Texas, United States |
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| | Albert Einstein College of Medicine – New York, New York, United States |
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