 | | Vol. 6.34 – 4 October, 2021 |
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| Scientists analyzed key parameters of endothelial function after exposure to aqueous smoke extracts of a heated tobacco product, an electronic cigarette, a conventional cigarette and pure nicotine.
[Redox Biology] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| The authors showed that the number of endothelial progenitor cells (EPCs) in hypertensive patients was significantly lower than that of normal population, and the cell function decreased with a higher proportion of EPCs at later stages.
[Pharmacological Research] |
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| Investigators assessed the therapeutic potential of dihydroceramide desaturase 1 inhibition, the last enzyme involved in de novo ceramide synthesis, to mitigate the vascular effects of the protein-bound uremic toxins indoxyl sulfate
[Vascular Pharmacology] |
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| Researchers demonstrated that the administration of cyclophilin A, a ligand of basigin which was expressed in barrier-forming endothelial cells, realized the artificial opening of blood–brain barrier.
[Scientific Reports] |
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| Four groups of electrospun nanofibrous scaffolds were compared: polycaprolactone (PCL), PCL/collagen, PCL/gelatin and PCL/chitosan. Each of the scaffolds were tissue-engineered with human corneal endothelial cells and analyzed with regard to their potential application as artificial posterior lamellar grafts.
[Scientific Reports] |
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| Scientists examined the involvement of advanced glycation end (AGE)-related receptors on AGE-induced angiogenesis in endothelial cells.
[Experimental Cell Research] |
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| The authors investigated the effect of crosstalk between retinal pigment epithelial (RPE) cells and choroidal endothelial cells via the ANXA1/FPR2/NLRP3 inflammasome/pyroptosis axis on the development of choroidal neovascularization in vitro and in vivo.
[Inflammation] |
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| The proangiogenic effect of bovine milk exosomes was analyzed both in isoproterenol-induced cardiac fibrosis rats in vivo and in HUVECs after oxygen and glucose deprivation in vitro.
[Journal of Cardiovascular Translational Research] |
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| Researchers found that NAMPT overexpression protected human coronary artery endothelial cells from H2O2-induced injury through promoting cell viability, inhibiting cell apoptosis, enhancing cell motility, and promoting tube formation.
[Journal of Cardiovascular Pharmacology] |
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| Further preclinical and clinical studies will explore defibrotide’s potential utility in a broader range of disorders resulting from endothelial cell activation and dysfunction.
[Bone Marrow Transplantation] |
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| Baxter International, Inc. announced the US FDA approval and commercial launch of premix Norepinephrine Bitartrate in 5% Dextrose Injection.
[Baxter International, Inc.] |
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| October 26 – 28, 2021
Virtual |
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| Radboud University Medical Centre – Nijmegen, Netherlands |
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| The University of New Mexico – Albuquerque, New Mexico, United State |
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| | The University of New Mexico – Albuquerque, New Mexico, United States |
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| | The University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | University of Southern California – Los Angeles, California, United States |
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