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| In liver sinusoidal endothelial cells in vitro, stimulation or inhibition of ALK1 signaling counter-regulated Inhibitors of DNA binding 1-3, known Alk1 transcriptional targets.
[Hepatology] |
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|
 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Surface adhesion micropatterns were used to control the adhesion of endothelial cells within adjacent hexagonal microstructures to promote the emergence of a well-controlled and standardized cell layer phenotype onto surface plasmon resonance sensor surfaces.
[Biosensors & Bioelectronics] |
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| Investigators found that exposing the endothelium-lined channel to fluid flow led to increased secretion of regeneration-associated factors.
[Proceedings of the National Academy of Sciences of the United States of America] |
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| Scientists investigated the role of epithelial-stromal interaction 1 (EPSTI1) in monocyte-endothelial cell adhesion and its expression pattern in atherosclerotic plaques.
[Acta Pharmacologica Sinica] |
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| The authors showed that aiphanol dose-dependently counteracted VEGF-C-induced proliferation, migration, and tubular formation of lymphatic endothelial cells, which was further verified in vivo.
[Acta Pharmacologica Sinica] |
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| Researchers showed that progenitor exosomal communication across embryonic organs occured in normal development and was altered in embryos of diabetic pregnancy.
[Communications Biology] |
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| Scientists reported a strategy to rejuvenate circulating vascular progenitor cells by conjugation of drug-loaded liposomal nanoparticles directly to the surface of gestational diabetes mellitus-exposed endothelial colony-forming cells.
[Communications Biology] |
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| Investigators found that the association between mesoglycan/VEGF had a strong pro-healing activity. In detail, this combination induced angiogenesis in human endothelial cells promoting in turn fibroblasts recruitment.
[Scientific Reports] |
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| Researchers identified that black carbon induced mitochondrial damage and suppressed autophagy function in EA.hy926 cells, as evidenced by elevation of the aspartate aminotransferase, reactive oxygen species, and p62, and the reduction of mitochondrial membrane potential.
[Environmental Toxicology] |
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| The authors summarize the abnormal cells — epithelial cells, endothelial cells, immune cells, and fibroblasts — and their interactions in fibrosis.
[Signal Transduction and Targeted Therapy] |
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| Regeneron Pharmaceuticals, Inc. announced the US FDA has accepted for review the EYLEA® Injection supplemental Biologics License Application for an every 16-week 2 mg dosing regimen in patients with diabetic retinopathy.
[Regeneron Pharmaceuticals, Inc.] |
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| December 3 – 7, 2022
Washington, DC, United States |
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| | University of Oslo – Oslo, Norway |
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| | The University of Tennessee Health Science Center – Memphis, Tennessee, United States |
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| | University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | Aarhus University – Aarhus, Denmark |
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| | University of California, San Diego – La Jolla, California, United States |
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