 | | Vol. 17.15 – 20 April, 2022 |
| |
|
|
| Researchers identified cells with characteristics of lacrimal gland primordia that emerged in 2D eye-like organoids cultured from human PSCs.
[Nature] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| The authors employed the naive-to-primed transition of human PSCs to model peri-implantation epiblast development.
[Cell Stem Cell] |
|
|
|
| Scientists endogenously introduced TIN2-dyskeratosis congenita (DC) mutations in human ESCs and human hematopoietic stem and progenitor cells to dissect the disease mechanism and identified a gene editing strategy that rescued the DC phenotypes.
[Blood] |
|
|
|
| Investigators showed that hPSCs failed to differentiate and contributed teratoma in the presence of mouse PSCs, while MYCN, a pro-growth factor, dramatically promoted hPSC contributions in teratoma co-formation by hPSCs/mPSCs.
[Stem Cell Reports] |
|
|
|
| Researchers discovered that YY1 bound to specific open chromatin regions in extended pluripotent stem cells (EPSCs). Yy1 depletion in EPSCs led to a gene expression pattern more similar to that of ESCs than control EPSCs.
[Nucleic Acids Research] |
|
|
|
| Investigators showed that SOX2, which plays a key role in maintaining the pluripotency of stem cells, was critical for human endogenous retroviruses-K LTR5Hs.
[Journal of Virology] |
|
|
|
| The construction of iPSCs from two spinal cerebellar ataxia type 3 (SCA3) patients (14/74 CAG repeats) may serve as an excellent tool for studying SCA3 disease mechanisms and for drug screening.
[Stem Cell Research] |
|
|
|
| Researchers reported that a 3D culture of mouse ESCs could generate hypothalamic-like tissues containing melanin-concentrating hormone (MCH)-positive neurons, which reproduced morphologic maturation, neuronal connectivity, and neuropeptide/neurotransmitter phenotype of native MCH neurons.
[eNeuro] |
|
|
|
| iPSC-derived type 2 alveolar epithelial cells could be generated through a directed differentiation protocol that recapitulated in vivo lung development
[Developmental Biology] |
|
|
|
|
| Levels of telomerase RNA and dyskerin, encoded by DKC1, are known to limit telomerase activity in ESCs. X-linked DKC1 is expressed from both alleles in female embryo cells and higher levels of dyskerin and telomerase could elongate telomeres prior to embryo implantation.
[Aging Cell] |
|
|
|
| Scientists address the current advance in the derivation of male germ cells in vitro from stem cells based on studies, and highlight the perspectives and potential application of stem cell-derived male gametes in reproductive medicine.
[Asian Journal of Andrology] |
|
|
|
|
| Researchers at Cedars-Sinai are launching their expertise into space to see if they can elevate the next generation of stem cell and gene therapies by harnessing the near-zero gravity conditions of spaceflight.
[Cedars Sinai] |
|
|
|
| TreeFrog Therapeutics announced the launch of The Stem Cell SpaceShot Grant, a $100,000 research funding in the field of stem cell biology and regenerative medicine.
[TreeFrog Therapeutics] |
|
|
|
|
| June 12 – 16, 2022
Keystone Symposia, Colorado, United States |
|
|
|
|
|
| | Albert Einstein College of Medicine – New York, New York, United States |
|
|
|
| | University of Gothenburg – Gothenburg, Sweden |
|
|
|
| | Harvard University – Cambridge, Massachusetts, United States |
|
|
|
| | Baylor College of Medicine – Houston, Texas, United States |
|
|
|
| | Baylor College of Medicine – Houston, Texas, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
