 | | Vol. 17.24 – 22 June, 2022 |
| |
|
|
| The authors generated >90% pure human artery or vein endothelial cells from PSCs within three to four days and specified artery cells by inhibiting vein-specifying signals and vice versa.
[Cell] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Scientists showed that the coordinated expression of pluripotency markers defined epiblast identity. Conversely, inner cell mass progenitor cells displayed random cell-to-cell variability in expression of various pluripotency markers.
[Nature Communications] |
|
|
|
| Researchers reported that major satellite repeats transcripts could drive the formation of HP1É‘ droplets in vitro, and modulated heterochromatin into dynamic condensates in ESCs, contributing to the formation of large nuclear domains that were characteristic of pluripotent cells.
[Nature Communications] |
|
|
|
| Investigators reexamined BABY BOOM expression and function in the model plant Arabidopsis thaliana using reporter analysis and newly developed CRISPR mutants.
[Proceedings of the National Academy of Sciences of the United States of America] |
|
|
|
| Scientists reported that chemical blockage of ACTIVIN/NODAL and FGF signals was sufficient to steer human primed ESCs into GATA3-expressing cells that gave rise to placental hormone-producing syncytia.
[Cell Reports] |
|
|
|
| The authors explored the effects of exosomes produced by iPSCs-derived keratinocytes in a model of deep second-degree burn wound healing and evaluated the mechanistic basis for the observed activity.
[Journal of Nanobiotechnology] |
|
|
|
| Researchers demonstrated that homozygous knockout of Hbxip led to embryonic lethality, with retarded growth around E7.5, and that depletion of Hbxip compromised the self-renewal of ESCs.
[Development] |
|
|
|
| Scientists tested a highly sensitive and non-disruptive quality-testing method that involved measuring miRNAs in culture supernatants released by cells.
[Scientific Reports] |
|
|
|
| Using standard CDM3 differentiation protocols, gene expression profiles demonstrated that hiPSC-derived cardiomyocytes did not progress past the equivalent of embryonic day 14.5 of murine cardiac development.
[Stem Cells and Development] |
|
|
|
|
| The authors summarize the current state of affairs of hiPSCs and automated patch clamps: the background and recent advances made, and the pros, cons, and challenges of these technologies.
[Frontiers in Molecular Neuroscience] |
|
|
|
| Scientists review published papers containing data from recent clinical trials done with PSCs.
[Regenerative Medicine] |
|
|
|
|
| The University of Rochester Medical Center (URMC) and Sana Biotechnology have entered into an agreement which will allow Sana to expand its manufacturing footprint and create new job opportunities in Rochester.
[The University of Rochester Medical Center] |
|
|
|
|
| December 3 – 7, 2022
Washington, DC, United States |
|
|
|
|
|
| | The University of Arizona – Tucson, Arizona, United States |
|
|
|
| | Yale University – New Haven, Connecticut, United States |
|
|
|
| | Baylor College of Medicine – Houston, Texas, United States |
|
|
|
| | University of Cambridge – Cambridge, England, United Kingdom |
|
|
|
| | Flanders Institute for Biotechnology – Antwerp, Belgium |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
