 | | Vol. 18.22 – 07 June, 2023 |
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LIS1 RNA-Binding Orchestrates the Mechanosensitive Properties of Embryonic Stem Cells in AGO2-Dependent and Independent Ways | The authors showed that LIS1 was essential for the viability of mouse ESCs, and it governed the physical properties of these cells.
[Nature Communications] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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On-Chip Real-Time Impedance Monitoring of hiPSC-Derived and Artificial Basement Membrane-Supported Endothelium | Researchers constructed a model to explore the effect of stiffness changes in mouse trophoblast stem cells (mTSCs) on implantation: microcarrier was prepared by sodium alginate using a droplet microfluidics system, and mTSCs were attached to the microcarrier surface with laminin modifications, called T(micro).
[Bioactive Materials] |
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The Circadian Clock CRY1 Regulates Pluripotent Stem Cell Identity and Somatic Cell Reprogramming | Reprogramming somatic cells to a pluripotent state, the authors highlighted non-canonical functions of the circadian repressor Cryptochrome 1 (CRY1) specific to PSCs.
[Cell Reports] |
| Suspension Culture Improves iPSC Expansion and Pluripotency Phenotype | Sendai virus transfection of human peripheral blood mononuclear cells was used to establish mycoplasma and virus free iPSC lines without common genetic duplications or deletions. iPSCs were then expanded under 2D planar and 3D suspension culture conditions.
[Stem Cell Research & Therapy] |
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iPSCs Ameliorate Hypoxia-Induced Autophagy and Atrophy in C2C12 Myotubes via the AMPK/ULK1 Pathway | Investigators co-cultured iPSCs with C2C12 myoblasts using a Transwell nested system and placed them in a DG250 anaerobic workstation for oxygen deprivation for 24 hours.
[Biological Research] |
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Identification and Functional Evaluation of Alternative Splice Variants of Dax1 in Mouse Embryonic Stem Cells | Scientists identified 18 new transcripts of Dax1 with putative protein-coding properties, and compared their proteins structures with known Dax1 protein.
[Stem Cells And Development] |
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A Monoclonal Antibody Raised against Human EZH2 Cross-Reacts with the RNA-Binding Protein SAFB | The authors reported that a broadly used rabbit monoclonal antibody raised against human EZH2 cross-reacted with an RNA-binding protein called Scaffold Attachment Factor B (SAFB) in mouse ESCs under buffer conditions that are commonly used for chromatin immunoprecipitation.
[Biology Open] |
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GSK-3α/β and MEK Inhibitors Assist the Microenvironment of Tumor Initiation | Human iPSCs reprogrammed from monocytes of healthy volunteers were cultured in a media containing 50% of the conditioned medium from human pancreatic cancer derived BxPC3 cells supplemented with a MEK inhibitor and a GSK-3α/β inhibitor.
[Cytotechnology] |
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Generation of an Induced Pluripotent Stem Cell Lines NSHDMUi001-A from Patients with Type 2 Diabetes | The authors reprogrammed pEP4EO2SEN2K and pEP4EO2SET2K, pCEP4-M2L was electrotransfected in Type 2 diabetes mellitus (T2DM) patients with pEP4EO2SEN2K, and in T2DM patients expressing the OCT4, SOX2, NANOG, LIN28, c-MYC, KLF4, and SV40LT transcription factors to obtain iPSCs.
[Stem Cell Research] |
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Human Embryo Implantation | Investigators examine the evolutionary context of embryo implantation and elaborate on uterine remodeling before and after conception in humans.
[Development] |
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Harnessing Three-Dimensional (3D) Cell Culture Models for Pulmonary Infections: State of the Art and Future Directions |
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Mammalian embryonic and induced pluripotent stem cells may display their remarkable self-organizing abilities in 3D culture, and the resulting organoids replicate important structural and functional characteristics of organs such the kidney, lung, gut, brain, and retina.
[Naunyn-Schmiedebergs Archives Of Pharmacology] |
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| UCR’s Stem Cell Research Program Cashes In | The University of California, Riverside (UCR) gains $2.9 million dollars from the California Institute for Regenerative Medicine for the Research Training and Mentorship Program Inspire Diverse Undergraduates toward Regenerative Medicine Careers, otherwise known as RAMP.
[University of California, Riverside (The Highlander)] |
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AACR Special Conference: Ovarian Cancer | October 5 – 7, 2023
Boston, Massachusetts, United States |
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| | University of Cambridge – Cambridge, England, United Kingdom |
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| | Sheffield University – Sheffield University, England, United Kingdom |
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| | Babraham Institute – Cambridge, England, United Kingdom |
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| | University of California – Oakland, California, United States |
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| | Babraham Institute – Cambridge, England, United Kingdom |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
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Pancreatic Cell News
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