 | | Vol. 18.24 – 21 June, 2023 |
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| By performing genome-wide CRISPR interference screens in human and chimpanzee PSCs, scientists identified 75 genes with species-specific effects on cellular proliferation.
[Cell] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| The authors used mouse embryonic stem cell-derived stembryos to understand the mechanism underlying the Hox timer.
[Nature Genetics] |
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| Using in vitro differentiation of PSCs, researchers recapitulated the segmentation clocks of diverse mammalian species varying in body weight and taxa: marmoset, rabbit, cattle, and rhinoceros.
Cell Stem Cell] |
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| Investigators identified the unexpected role of a highly expressed 2-cell embryo specific transcription factor, ZFP352, in facilitating the dissolution of the totipotency network.
[Nature Communications] |
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| The authors showed that methyltransferase-like 14 (METTL14) specifically bound and regulated bivalent domains, which were marked by trimethylation of histone H3 lysine 27 and lysine 4.
[Cell Reports] |
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| The dynamic H4K20me3 signature identified during preimplantation development in fertilized embryos differed from nuclear transfer and parthenogenetic activation embryos.
[Cell Proliferation] |
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| Since no information is available about the capability of female human adipose-derived mesenchymal stromal cells (hASCs) to generate putative primordial germ cells, scientists compared protocols to produce such cells from hASCs themselves, or from hASC-derived iPSCs.
[Stem Cell Reviews And Reports] |
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| Colonies formed by mouse ESCs carrying OGTC921Y showed decreased levels of protein O-GlcNAcylation accompanied by decreased levels of Oct4, Sox2, and extracellular alkaline phosphatase, implying reduced self-renewal capacity.
[Disease Models & Mechanisms] |
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| Scientists showed in a unique site-directed knock-in ESC model, that BCR-ABL expression tightly regulated by doxycycline controlled the formation and the maintenance of immature hematopoietic progenitors.
[Experimental Hematology] |
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| The authors discuss the relevant cell types and cell sources and examine different co-culture approaches for skeletal muscle and adipose tissue engineering.
[Nature Reviews Bioengineering] |
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| Two teams of scientists have announced that they have grown embryo-like structures, made entirely from human stem cells, that are more advanced than any previous efforts.
[Nature News] |
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| October 18 – 21, 2023
EMBL Heidelberg and Virtual |
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| | The University of Texas M. D. Anderson Cancer Center – Houston, Texas, United States |
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| | University Hospital RWTH Aachen – Aachen, Germany |
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| | The University of California San Francisco – San Francisco, California, United States |
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| | Human Technopole – Milan, Italy |
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| | Virginia Tech – Washington, DC, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
