 | | Vol. 18.33 – 6 September, 2023 |
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| Human fully integrated mouse Structured Stem cell-based Embryo Models with spatially organized morphogenesis recapitulated the organization of nearly all known lineages and compartments of post-implantation human embryos.
[Nature] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| The authors showed that Mcm2-mutated or Pole3-deleted mouse embryonic stem cells (ESCs) displayed aberrant histone landscapes and impaired neural differentiation.
[Nature Genetics] |
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| Researchers showed that Ascl1 and Ngn2 induced mutually exclusive side populations by binding and activating distinct lineage drivers.
[Nature Communications] |
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| Scientists generated a human astrocyte model carrying the APOE3 or APOE4 genotype using hiPSCs in which isogenic APOE4 iPSCs were genome edited from healthy control APOE3 iPSCs.
[Stem Cell Reports] |
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| Investigators described a method to improve iNeutrophil differentiations through the deletion of GATA1. GATA1 knockout iNeutrophils were nearly identical to primary neutrophils in form and function.
[iScience] |
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| The authors identified that DAXX, an H3.3 chaperone essential for the maintenance of ESCs in the ground state, accumulated in pericentromeric regions independently of DNA methylation.
[Journal Of Cell Science] |
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| Researchers generated an iPSC line from a patient with epileptic encephalopathy caused by the CYFIP2 R87C variant. They obtained iPSC clones by reprogramming urinary progenitor cells from a female patient.
[Human Cell] |
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| Using a deconvolution algorithm that employs pooled sequencing of single-nucleotide polymorphisms, scientists accurately estimated individual donor proportions of the pooled iPSCs.
[Stem Cell Reports Methods] |
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| The authors established a bleomycin (BLM)-induced pulmonary fibrosis mice model and administered human embryonic stem cell exosomes from the first day after BLM treatment.
[Current Stem Cell Research & Therapy] |
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| Recent technological advances have unveiled molecular features that characterize totipotent cells. Single-cell or low-input sequencing technologies allow the dissection of pre- and post-fertilization developmental processes at the molecular level with high resolution.
[Life Science Alliance] |
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| KAN Research Trust, promoted by Indian entrepreneur Ashok Soota and the UK-based Wellcome-MRC Cambridge Stem Cell Institute, is all set to bring to India cutting-edge expertise in stem cell research through a series of partnership agreements that were concluded today in Cambridge.
[SKAN Research Trust] |
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| September 22 – 24, 2023
Ribeirao Preto, Brazil |
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| | Boehringer Ingelheim International – Biberach, Germany |
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| | Royal Infirmary – Edinburgh, Scotland, United Kingdom |
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| | Royal Infirmary – Edinburgh, Scotland, United Kingdom |
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| | Amgen – Burnaby, British Columbia, Canada |
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| | RareCyte – Seattle, Washington, United States |
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