 | | Vol. 18.23 – 14 June, 2023 |
| |
|
|
| Investigators explored whether the human trophoblast stem cells state could be induced independently of pluripotency, and what were the mechanisms underlying its acquisition.
[Nature Communications] |
|  |
|
|
| PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Researchers generated a mouse-iPSC line carrying a lung-specific mesenchymal reporter/lineage tracer. They identified the pathways necessary to specify lung mesenchyme.
[Nature Communications] |
|
|
|
| The authors showed the utility of village models, demonstrating how cells could be assigned to an iPSC line using single-cell sequencing and illustrating that the genetic, epigenetic, or induced PSC line-specific effects explained a large percentage of gene expression variation for many genes.
[Nature Communications] |
|
|
|
| Scientists systematically compared the effects of various culture conditions on the pluripotency and cell fate in vivo of mouse ESCs by tetraploid embryo complementation assay.
[Cell Reports] |
|
|
|
| Data suggested a model where serine-arginine rich splicing factor 3 (SRSF3) binding, and potentially its RS-domain interactions, may facilitate an RNA structure that promoted miR-17-92 processing.
[EMBO Reports] |
|
|
|
| The authors described the development of a TBX5/MYL2 lineage tracing reporter system that allowed for the identification of FHF- progenitors and their descendants including left ventricular cardiomyocytes.
[eLife] |
|
|
|
| The activity and expression of transient receptor potential ankyrin 1 (TRPA1) in ESC-cardiomyocytes was modulated by pharmacological or molecular approaches. Knockdown or overexpression of genes was done by infection of cells with adenoviral vectors carrying the gene of interest as a gene delivery tool.
[Stem Cell Research & Therapy] |
|
|
|
| Building on prior work that established the suitable non-basal medium components for hiPSC growth, investigators developed a simplified basal medium consisting of just 39 components.
[Stem Cell Reports] |
|
|
|
| Researchers determined the interaction between exogenous and endogenous stem cells during bone healing using a standardized burr-hole bone injury model in a mesenchymal progenitor cell lineage-tracing mouse under normal homeostatic and osteoporotic conditions.
[Scientific Reports] |
|
|
|
| iPSC derived macrophage and dendritic like cells were compared to CD34+ hematopoietic stem cell derived populations using transcriptomic analysis.
[Scientific Reports] |
|
|
|
|
| The authors review and propose approaches in utilizing PSCs for screening of the impact of environmental chemicals on the development of dopaminergic neurons. Related techniques and gaps in knowledge are also addressed.
[Stem Cell Reviews And Reports] |
|
|
|
|
| Many U.S. biomedical researchers and their collaborators abroad are reacting with alarm to a new NIH requirement that foreign groups send their NIH partners copies of their lab notebooks and other raw data at least every few months.
[Science Insider] |
|
|
|
|
| July 17 – 20, 2023
Burlington, Vermont, United States |
|
|
|
|
|
| | Human Technopole – Milan, Italy |
|
|
|
| | University of Cambridge – Cambridge, England, United Kingdom |
|
|
|
| | Virginia Tech – Washington, DC, United States |
|
|
|
| | Massachusetts Institute of Technology – Cambridge, Massachusetts, United States |
|
|
|
| | Center for Disease Neurogenomics at the Icahn School of Medicine – Manhattan, New York, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
