 | | Vol. 19.12 – 3 April, 2024 |
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| Researchers showed that a cell population located in the lateral region of the neural plate had properties resembling those of vertebrate neural-crest cells and neuromesodermal progenitors.
[Nature Ecology & Evolution] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators uncovered the post-translational modification (PTM) profiling of CCCTC-binding factor (CTCF) and demonstrated that CTCF could be O-GlcNAcylated and arginine methylated.
[Nature Communications] |
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| Scientists assessed the nanotoxicity of cerium oxide nanozymes and their potential antioxidant benefits in stressed hESCs and their derived cardiomyocytes.
[Journal of Nanobiotechnology] |
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| The authors established SFTPCGFP and AGERmCherry-HiBiT dual-reporter iPSCs, which detected alveolar type 2 (AT2)-to-alveolar type 1 (AT1) cell differentiation with high sensitivity and identified factors inducing AT1 cell differentiation from AT2 and their progenitor cells.
[Stem Cell Reports] |
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| Investigators showed that the loss of chromosome 18q impaired neuroectoderm commitment and that downregulation of SALL3, a gene located in the common 18q loss region, was responsible for this failed neuroectodermal differentiation.
[Stem Cell Reports] |
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| Researchers defined the transcriptional consequences of TBXT dosage reduction during early human gastrulation using hiPSC models of gastrulation and mesoderm differentiation.
[Development] |
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| The authors edited the AG bases in exons anterior to achieve gene knockout via the ABE8e-SpRY, which recognized most expanded protospacer adjacent motif to target the genome.
[Stem Cell Reviews and Reports] |
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| A chemical-defined protocol was successfully developed for the differentiation of functional corneal endothelial-like cells derived from hESC.
[Experimental Eye Research] |
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| Researchers reported a detailed method of generating rat iPSCs with improved reprogramming efficiency and differentiation into neurons.
[Journal of Neuroscience Methods] |
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| Investigators focus on chondrogenic differentiation and 3D bioprinting technologies using hiPSCS, suggesting them as a viable source for successful tissue engineering.
[Bioscience Reports] |
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| A rodent with two extra limbs instead of genitals shows the crucial role of a gene pathway in determining the fate of a primordial structure.
[Nature] |
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| | Sapienza University – Rome, Italy |
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| | NYU Langone Health – New York City, New York, United States |
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| | St. Anna Children’s Cancer Research Institute – Vienna, Austria |
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| | French National Institute for Health Research (INSERM) – Nantes, France |
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