 | | Vol. 19.14 – 17 April, 2024 |
| |
|
|
| Investigators revealed that MgFe-layered double hydroxide (LDH) had bidirectional regulatory effects on the differentiation of mESCs into neural progenitor cells, essentially suppressing cell differentiation on the first day and promoting cell differentiation on the third day.
[Advanced Functional Materials] |
|  |
|
|
| PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Researchers recovered 75,218 single cell transcriptomes of the highly regenerative and asexually-reproducing annelid Pristina leidyi.
[Nature Communications] |
|
|
|
| Scientists combined single-cell RNA-Seq and metabolic labeling to capture temporal cellular transcriptomes of zebrafish embryos where newly-transcribed and pre-existing mRNA could be distinguished.
[Nature Communications] |
|
|
|
| Investigators identified mechanisms that subsequently regulated germ plasm assembly in the early embryo. They showed that the Smaug RNA binding protein was transported into the germ plasm of the early embryo where it accumulated in the germ granules.
[Science Advances] |
|
|
|
| Researchers systematically screened factors essential for ESC pluripotency, identifying transcriptional enhanced associate domain (TEAD) 2 as an ancillary factor maintaining ground-state pluripotency in 2i/leukemia inhibitory factor (LIF) ESCs and facilitating the transition from serum/LIF to 2i/LIF ESCs.
[EMBO Journal] |
|
|
|
| The authors developed and characterized a 3D culture of self-renewing mouse embryonic cells that captured the main transcriptional and architectural features of the early gastrulating mouse epiblast.
[Developmental Cell] |
|
|
|
| In the selection of low- and high-density inoculation conditions, scientists found that low-density culture performed better in the final red blood cell product with more cell output and increased average cellular hemoglobin content.
[Stem Cells and Development] |
|
|
|
| Researchers investigated the effects of acetaldehyde dehydrogenase 2 (ALDH2) mutations on bone remodeling. They examined the effects of ALDH2 polymorphisms on in vitro osteogenesis using hiPSCs.
[International Journal of Stem Cells] |
|
|
|
|
| Recent high-throughput sequencing studies have revealed that mosaicism is common, clone sizes often increase with age and specific variants can affect tissue function and disease development.
[Nature Genetics] |
|
|
|
| The authors provide an update with a focus on H3.3 functions in early mammalian development, considering the context of ESC maintenance and differentiation, to finally conclude with emerging roles in cancer development and cell fate transition and maintenance.
[Trends in Cell Biology] |
|
|
|
|
| SCG Cell Therapy and the Agency for Science, Technology and Research (A*STAR) announced the launch of joint laboratories for cellular immunotherapies. This collaboration aims to advance the development of iPSC technology to produce novel cell therapies that meet GMP standards.
[SCG Cell Therapy] |
|
|
|
|
| May 7-11, 2024
Baltimore, Maryland, USA |
|
|
|
|
|
| | St. Jude Children’s Research Hospital – Memphis, Tennessee, United States |
|
|
|
| | Harvard Medical School and Brigham and Women’s Hospital – Boston, Massachusetts, United States |
|
|
|
| | Harvard University – Cambridge, Massachusetts, United States |
|
|
|
|
| | Sapienza University – Rome, Italy |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
