CURRENT PUBLICATIONS (Ranked by Impact Factor of the Journal) Patient-Specific Pluripotent Stem Cells Become Even More Accessible Researchers describe the derivation of human iPSCs from peripheral blood. Although seemingly incremental, this advance brings the stem cell field an important step closer to eventual clinical use. [Cell Stem Cell] Epigenetic Priming of a Pre-B Cell-Specific Enhancer through Binding of Sox2 and Foxd3 at the ESC Stage Here, researchers show that the embryonic stem cell (ESC) factor Sox2 targets H3K4 methylation to monovalent and bivalent domains. [Cell Stem Cell] Pax6 Is a Human Neuroectoderm Cell Fate Determinant Here, researchers show that Pax6 is uniformly expressed in early neuroectoderm cells of human fetuses and those differentiated from human embryonic stem cells. [Cell Stem Cell] When Fibroblasts MET iPSCs Two independent studies suggest that a mesenchymal-to-epithelial transition is a critical initiating event during the derivation of induced pluripotent stem cells (iPSCs) from fibroblasts, indicating remarkable similarities between cellular reprogramming, development, and cancer. [Cell Stem Cell] What Can Pluripotent Stem Cells Teach Us About Neurodegenerative Diseases? Here, researchers discuss the challenges of generating specific neural cell subtypes from pluripotent stem cells, the use of pluripotent stem cells to model both cell-autonomous and non-cell-autonomous mechanisms of neurodegeneration, whether adult-onset neurodegeneration can be emulated in short-term cultures and the hurdles of cell replacement therapy. [Nat Neurosci] The Long-Term Survival of In Vitro Engineered Nervous Tissue Derived from the Specific Neural Differentiation of Mouse Embryonic Stem Cells Researchers have established stable and long-term three-dimensional culture conditions which can be used to model long latency and complex neurodegenerative diseases. [Biomaterials] Differentiation of Rat Multipotent Adult Progenitor Cells to Functional Hepatocyte-Like Cells by Mimicking Embryonic Liver Development The protocol described here, sequentially using cytokines that are known to have a role in liver embryonic development, efficiently differentiates rat multipotent adult progenitor cells to hepatocyte-like cells by directing them through defined embryonic intermediates, namely, primitive streak/mesendoderm/definitive endoderm, hepatoblast and hepatocyte-like phenotype. [Nat Protoc] Induction of Pluripotent Stem Cells from Human Third Molar Mesenchymal Stromal Cells Researchers generated induced pluripotent stem cells from mesenchymal stromal cells derived from human third molars (wisdom teeth) by retroviral transduction of OCT3/4, SOX2, and KLF4 without MYC which is considered as oncogene. [J Biol Chem] Response of Human Embryonic Stem Cells (hESCs) Derived Mesenchymal Stem Cells to Osteogenic Factors and Architectures of Materials during In Vitro Osteogenesis In this study, homogenous hESCs derived mesenchymal stem cells were generated and used to construct bone tissue. [Tissue Eng Part A]
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INDUSTRY NEWS Stem-Cell Furore Erupts Long-rumbling hostilities between stem-cell researchers in Germany exploded into a blazing public row, after Nature published a critical reanalysis of data from a high-profile 2008 article. [Nature News Press Release] NeoStem Adds Distinguished Researcher to its World-Class Scientific Advisory Board NeoStem, Inc. announced that it has appointed Roberto Bolli, M.D., to its Scientific Advisory Board. Dr. Bolli has produced an immense body of stem-cell research, including work emphasizing the ability of very small embryonic-like stem cells to regenerate and repair after myocardial infarction. [NeoStem, Inc. Press Release] $6M Award to Support Aging Resource at Coriell Institute Close on the heels of another major award from the National Institutes of Health (NIH), the Coriell Institute has announced its receipt of a five-year, $6-million NIH contract to manage the National Institute on Aging (NIA) Aging Cell Repository. [Coriell Institute for Medical Research Press Release] Fate Therapeutics Receives Red Herring’s North America 100 Award for Advancing Stem Cell Technology and New Medicines Therapeutics, Inc. announced that the Company received Red Herring’s North America 100 award, a prestigious list honoring the year’s most promising private and innovative companies from the North American business region. [Fate Therapeutics, Inc. Press Release]
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EVENTS United Kingdom National Stem Cell Network (UKNSCN) 3rd Annual Scientific Conference July 12-14, 2010 Nottingham, United Kingdom
2nd International Conference on Cellular and Molecular Bioengineering (ICCMB2) August 2-4, 2010 Singapore
Select Biosciences 3rd Annual Stem Cells Europe Conference August 24-25, 2010 Edinburgh, Scotland Select Biosciences Inaugural Cellular Therapy Summit August 24-25, 2010 Edinburgh, Scotland
International Society for Cellular Therapy (ISCT) – Europe 2nd Regional Meeting September 11-14, 2010 Belgirate, Italy
Stem Cells USA & Regenerative Medicine Congress 2010 September 13-15, 2010 Philadelphia, United States Tissue Engineering & Regenerative Medicine International Society (TERMIS) – Asia Pacific 2010 September 15-17, 2010 Sydney, Australia 5th World Congress on Preventive & Regenerative Medicine (WCRM) 2010 October 5-7, 2010 Hannover, Germany
Fraunhofer Life Science Symposium Leipzig 2010 October 29-30, 2010 Leipzig, Germany
Select Biosciences 2nd International Forum on Stem Cells November 12-13, 2010 Tianjin, China Stem Cell Network 10th Annual Scientific Meeting November 22-24, 2010 Calgary, Canada Tissue Engineering & Regenerative Medicine International Society (TERMIS) – North America 2010 Annual Conference December 5-8, 2010 Orlando, United States
Stem Cells World Congress January 24-25, 2011 San Diego, United States Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community.
JOB OPPORTUNITIES Senior Scientist – Magnetic Cell Separation (STEMCELL Technologies) Recruit Top Talent Reach more than 11,000 potential candidates by posting your organization’s career opportunities with ESC & iPSC News. Visit here to post your career opportunities. |
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