Programming Human Pluripotent Stem Cells into White and Brown Adipocytes Here researchers report the robust and efficient differentiation of human pluripotent stem cells into white or brown adipocytes. [Nat Cell Biol] Abstract Chondrogenic Differentiation of Induced Pluripotent Stem Cells from Osteoarthritic Chondrocytes in Alginate Matrix In the present study, researchers investigated the differentiation potential of osteoarthritic chondrocytes (OCs) into induced pluripotent stem cells (iPSCs) using defined transcription factors and explored the possibility of using these OC-derived iPSCs for chondrogenesis. [Eur Cell Mater] Abstract Nrf3-Pla2g7 Interaction Plays an Essential Role in Smooth Muscle Cell Differentiation from Stem Cells In this study, embryonic stem cells were cultivated on collagen IV-coated plates to allow smooth muscle cell differentiation. [Arterioscler Thromb Vasc Biol] Abstract VZV Infects Human Embryonic Stem Cell-Derived Neurons and Neurospheres, but Not Pluripotent Embryonic Stem Cells or Early Progenitors In the present study researchers examine whether pluripotent human embryonic stem cells and neural progenitors at intermediate stages of differentiation are permissive for varicella zoster virus infection. [J Virol] Abstract A Molecular Signature for Purified Definitive Endoderm Guides Differentiation and Isolation of Endoderm from Mouse and Human Embryonic Stem Cells Here, investigators describe purification of mouse definitive endoderm using fluorescence-activated cell sorting and mice harboring a transgene encoding enhanced green fluorescent protein inserted into the Sox17 locus, which is expressed in embryonic endoderm. [Stem Cells Dev] Abstract Generation and Characterization of Leukemia Inhibitory Factor-Dependent Canine Induced Pluripotent Stem Cells from Adult Dermal Fibroblasts In this study scientists describe the production of canine induced pluripotent stem cells from adult dermal fibroblasts. [Stem Cells Dev] Abstract Cycle Arrest and Aneuploidy Induced by Zidovudine in Murine Embryonic Stem Cells Researchers used murine embryonic stem cells as a model to investigate the consequences of zidovudine exposure for embryogenesis. [Mutagenesis] Abstract Evaluation of the Use of an Induced Pluripotent Stem Cell Sheet for the Construction of Tissue-Engineered Vascular Grafts In this study, investigators evaluated the use of a sheet created from induced puripotent stem cell-derived vascular cells as a potential source for the construction of a tissue-engineered vascular graft. [J Thorac Cardiovasc Surg] Abstract Mineralocorticoid Receptor Overexpression Facilitates Differentiation and Promotes Survival of Embryonic Stem Cell-Derived Neurons To investigate the impact of mineralocorticoid receptor (MR) in neuronal survival, investigators generated murine embryonic stem cells that overexpress human MR and are induced to differentiate into mature neurons. [Neuroendocrinology] Abstract A Method for Deriving Homogenous Population of Oligodendrocytes from Mouse Embryonic Stem Cells Researchers describe clear methodology for differentiation of mouse embryonic stem cells to oligodendrocyte to a high degree of homogenity and reproducibility in vitro. [Dev Neurobiol] Abstract |